四氧嘧啶致糖尿病大鼠喂含豌豆和陈皮饼干的可能影响

hanan shalaby, H. El-sayed
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引用次数: 0

摘要

蔬菜和水果果皮通常含有丰富的酚类物质,具有抗氧化特性,因此被认为是代谢综合征的治疗方法。本研究评价了豌豆陈皮粉中酚类化合物对糖尿病大鼠的健康作用。测定了裂解物的化学成分。选取健康成年雄性白化大鼠30只,随机分为5组(每组6只):1组以基础饲粮为阴性对照。其余各组皮下注射四氧嘧啶(150 mg/kg体重)诱导糖尿病。对照组(2)以正常饮食为阳性对照,对照组(3)以标准饮食和无皮饼干为阳性对照。4组和5组分别饲喂天然日粮和添加10%豌豆皮和陈皮的饼干,为期8周。此外,测定血清中葡萄糖、血脂、肝肾功能及检查组织。结果表明,陈皮具有最高的抗氧化活性和酚类化合物。豌豆皮的蛋白质和纤维含量最高,脂肪和水分含量最低。在饼干中加入10%的橘子皮和豌豆皮可以提高感官评价。陈皮、豌豆皮夹心饼能改善血糖、血脂、肝肾功能。与组(3)相比,组(4,5)的胰腺组织得到改善。因此,研究表明,含有10%豌豆和陈皮的饼干具有很高的提高营养价值和预防糖尿病疾病的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Conceivable Effect of feeding Crackers Containing Peas and Tangerine Peels on Rats with diabetes induced by alloxan
V egetable and fruit peels are commonly rich in phenolic with antioxidant properties so it considered metabolic syndrome remedies. This study was evaluated the phenolic compounds of peas and tangerinepeels powder may as beneficial health on diabetic rats were fed on crackers enrich with 10% from its.  The chemical compositionof crackers was determined. Thirty healthy adult male albino rats were separated into five groups (six rats each) as follows: Group (1) were fed on basal diet as negative control. Other groups were injected subcutaneous with Alloxan (150 mg/kg body weight) to induce diabetes. Group (2), received the normal diet as a positive control, Group (3) intake standard diet and crackers without peels. Groups (4 and 5)fed on natural diet and cracker with 10% peas and tangerine peels respectively for 8 weeks. In addition, glucose, lipid profile, liver and kidney functions were determined in serum and examination tissues were carried out. Results obtained that tangerine peels had the highest antioxidant activity and phenolic compounds. Pea’s peels were the highest value of protein and fiber while fat and moisture contents is the lowest. Enrichment of crackerswith 10% tangerine and pea’s peels caused increases in sensory evaluation. Cracker with tangerine and peas peels showed improve glucose, serum lipid profile, liver, kidney functions.  Pancreas tissues of groups (4, 5) were ameliorate compare with group (3). Thus, the study imagery those crackers containing 10% peas and tangerine peels exhibit high potential to enhance the nutritional value and protection against diabetes diseases.
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