公藤对前列腺癌细胞的抗氧化作用

Montasir Ahmed Elnour, Fatima Penech, Siddig Ibrahim, A. Khalid
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引用次数: 0

摘要

自古以来,植物就被用来治疗人类和动物的各种疾病。它们保持个体的健康和活力,也可以治疗疾病,包括癌症,而不会产生毒性。本文研究了抗炎、抗肿瘤常用的根、叶、茎的抗癌、抗氧化活性。采用80%甲醇提取各植物部位,采用MTT法检测其抗PC3(前列腺癌)活性,并通过检测植物甲醇提取物对全血吞噬细胞和活性氧产生的抑制作用及金属螯合活性测定其抗氧化活性,过滤保存,新鲜制备。提取物根对前列腺癌(PC3)的IC50值为24μg/ml。提取物叶、茎对PC3(前列腺癌)的ic50值分别>100、>100μg/ml。植物甲醇提取物对全血吞噬细胞和活性氧产生的抑制作用在研究的所有植物部位根、叶和茎中均无活性,ic50值>200。在浓度为50µg/mL时,甲醇提取物对金属螯合活性均有不同程度的抑制作用。根25.99µg / m。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Combretum Adenogonium Induce Anticancer and Antioxidant Effects in Prostate Cancer Cell Line
Plants have been used fortreating various diseases of human beings and animalssince time immemorial. They maintain the health andvitality of individuals, and also cure diseases, includingcancer without causing toxicity. This work investigated the anticancer, antioxidant activities of roots, leaves, and stems commonly used as anti inflammatory and anti tumor. All the plant parts were extracted using 80% methanol, the anticancer activity was examined by using MTT assay against PC3 (Prostate Cancer) and determine their antioxidant activities by testing Effect ofPlant Methanol Extracts on suppressing whole blood Phagocytes and ROS Production and Metal chelating activities, filter and kept in dark, prepared freshly. The extract roots, DC has shown very high activity against PC3 (Prostate Cancer) IC50 values 24μg/ml. The extract leaves, and stems has shown none active anti against PC3 (Prostate Cancer) IC 50 values >100, and >100μg/ml respectively. All the extracts Effect ofPlant Methanol Extracts on suppressing whole blood Phagocytes and ROS Production has shown none active in all plants parts under study roots, leaves, and stems IC 50 values>200 . All the examined plant methanol extracts showed different levels of inhibition % for their metal chelating activity at concentration 50µg/mL. roots 25.99µg/m.
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