与酵母线粒体核糖体蛋白Yml30基因同源的人类新基因C15或f4的克隆、定位及表达分析

DNA Sequence Pub Date : 2001-01-01 DOI:10.3109/10425170109047561

Laura Carim-Todd, L. Sumoy, N. Andreu, X. Estivill, M. Escarceller

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引用次数: 2

摘要

我们已经鉴定出C15orf4，一个新的人类基因显示同源酵母线粒体核糖体蛋白YmL30。C15orf4编码一个1006 nt的转录本，ORF为279个氨基酸，预测蛋白大小为31.7 kDa。C15orf4在睾丸中表达丰富。通过辐射杂交定位，将C15orf4定位到染色体15q24上。我们已经确定了C15orf4小鼠同源物以及其他物种的同源物。

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Cloning, Mapping and Expression Analysis of C15 or f4, a Novel Human Gene with Homology to the Yeast Mitochondrial Ribosomal Protein Yml30 Gene

We have identified C15orf4, a novel human gene showing homology to the yeast mitochondrial ribosomal protein YmL30. C15orf4 encodes a transcript of 1,006 nt with an ORF of 279 amino acids and a predicted protein size of 31.7 kDa. Expression of C15orf4 is enriched in testis. C15orf4 was positioned to chromosome 15q24 by radiation hybrid mapping. We have identified the C15orf4 mouse orthologue as well as homologues in other species.

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DNA Sequence

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