作为补充替代天然产品radioprotectores放疗肿瘤

Subhajit Dutta, Raju R Wadekar, Tilottama Roy
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引用次数: 4

摘要

当暴露于有害的电离辐射时,人类会患上各种病理生理障碍,包括癌症。放射治疗是一种用高能量波瞄准并杀死肿瘤内癌细胞的治疗方法。这种疗法非常昂贵,而且需要使用非常复杂的仪器。除此之外,包括氨磷汀在内的大多数合成辐射防护剂已被发现具有毒性。这促使研究人员开发出一种新的、经济上可行的、有效的替代放射治疗的治疗方法。在过去的二十年中,人们观察到研究天然产物作为辐射防护剂的重大转变,因为它们相对于许多现有的合成化合物具有潜在的生物等效性,因此非常有效。考虑到放射治疗的局限性,目前采用一种"综合肿瘤学"方法,将传统和常规医学治疗相结合,用于治疗患有癌症和相关精神和心理疾病的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Productos naturales radioprotectores como complementos alternativos en la radioterapia oncológica
Humans when exposed to harmful ionising radiations suffer from various pathophysiological disorders including cancer. Radiotherapy is a treatment where these cancerous cells within a tumor are targeted and killed by means of high energy waves. This therapy is very expensive and involves highly sophisticated instruments. In addition to this, most synthetic radioprotectors including Amifostine have been found to possess toxicity. This led researchers to develop a novel, economically viable, and efficient therapeutic alternative to radiation therapy. The last two decades have observed a major shift towards investigating natural products as radioprotectors, as these are immensely effective in terms of their potential bioequivalence relative to many of the established synthetic compounds available. Taking into account the limitations of radiation therapy, an approach ‘Integrative Oncology’ that involves a combination of both traditional and conventional medical treatment are used nowadays to treat patients suffering from cancer and associated mental and psychological disorders.
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