糖尿病的发病机制与治疗,问题与答案

D. Lu, Jin-Yu Che, Hong-ying Wu, Tingren Lu
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引用次数: 7

摘要

糖尿病是一种古老的现代流行病。近年来,尽管糖尿病的治疗取得了许多进步和益处,但在糖尿病的发病机制和治疗方面也发现了许多新的和尚未解决的问题;目前,糖尿病的发病机制和治疗研究还比较复杂和不完善。疾病并发症,如心血管症状、视力障碍、肾病、慢性腿部感染等,比控制高血糖更致命;此外,由于长期使用许多化学制剂和药物而产生的药物毒性对患者同样有害。此外,不同的医生和制药商对糖尿病的治疗方案和财务利益分布也有不同的看法。在这篇社论中,提出了建立更新的糖尿病治疗系统,新的药物开发管道和实验和临床模型的新思路,并强调了可能的未来方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Pathogenesis and Treatments of Diabetes, Questions and Answers
Diabetes Mellitus is an old disease but modern epidemics. Despite many improvements and benefits of diabetes mellitus treatments recently, many new and unresolved problems relevant to diabetes mellitus pathogenesis and therapy have been found; Pathogenesis and treatments study of diabetes currently is complicated and imperfect. Disease complications, such as cardiovascular symptoms, vision impairments, nephropathy, chronic leg infections etc are even more fatal than hyperglycemia control; Moreover, drug toxicities owing to long-term utilization of many chemical agents and drugs are equally harmful for patients. Furthermore, different doctors and drug manufactures hold different views on diabetes mellitus treatment options and financial interesting distributions. In this editorial, new ideas for building update diabetes mellitus therapeutic systems, new drug development pipelines and experimental and clinical models, possible future directions are proposed, addressed and highlighted.
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