C. De Voogt, G. Mampaey, G. Schils, P. Smets, L. Stammeleer
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引用次数: 0
摘要
一只三岁的雄性完整杰克罗素梗犬因严重再生性贫血被转诊,并被诊断为非相关免疫介导的溶血性贫血。按照ACVIM指南进行治疗(Swann et al., 2019)。尽管使用两种免疫抑制药物,11天后仍未见应答,因此静脉注射免疫球蛋白(IVIG, 1 g/kg)。3天后,感染性休克和弥漫性血管内凝血(DIC)发生。超声心动图显示心包积液伴心包填塞及右心房血栓。液体分析证实感染性心包炎在再次出现心包积液后立即进行心包引流。尽管IVIG给药后数天红细胞压积稳定,但随后发现红细胞压积下降,并进行脾切除术。总共输了6次血。两年后提出和强化随访,免疫抑制治疗逐渐减少,狗有很好的生活质量。
Septic pericarditis in a complicated case of non-associated immune-mediated hemolytic anemia in a Jack Russel terrier
A three-year-old, male, intact Jack Russel terrier was referred for severe regenerative anemia and was diagnosed with non-associated immune-mediated hemolytic anemia. Treatment was implemented according to the ACVIM guidelines (Swann et al., 2019). As no response was seen eleven days later despite two immunosuppressive drugs, intravenous immunoglobulins (IVIG, 1 g/kg) were administered. Three days later, septic shock and diffuse intravascular coagulation (DIC) developed. Echocardiography revealed pericardial effusion with cardiac tamponade and thrombus in the right atrium. Fluid analysis confirmed septic pericarditis. A pericardial drain was placed following immediate reoccurrence of the pericardial effusion. Despite a stable hematocrit for several days following IVIG administration, a decrease in hematocrit was subsequently noted and splenectomy was performed. In total, six blood transfusions were given. Two years after presentation and intensive follow-up, immunosuppressive therapy was tapered, and the dog had excellent quality of life.
期刊介绍:
The Vlaams Diergeneeskundig Tijdschrift (ISSN 0303-9021) is a scientific journal that is published bimonthly (six issues per year). It presents mainly clinical topics and addresses itself to two very different readerships: the local Dutch speaking veterinarians in Belgium and the Netherlands, and the international veterinary and biomedical research community. Each issue contains scientific papers either in English, or in Dutch with an English abstract.