全球猴痘病暴发:流行和治疗

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摘要

猴痘是一种人畜共患疾病,由猴痘病毒(MPXV)引起。它属于正痘病毒科的一种。来自多个来源的数据,包括流行病学研究、病例报告和临床试验,被纳入全面的文献分析。猴痘在中非和西非更为常见。此外,该病毒已在世界其他地区被发现,包括北美、欧洲和亚洲。发烧和明显的皮肤损伤,类似天花,是该病的主要症状。预防严重后果和二次传播需要早期诊断和有效护理。使用的主要治疗策略包括疫苗接种、抗病毒药物和支持性护理。尽管天花疫苗不是专门针对猴痘研制的,但在减少严重疾病方面已经显示出一些有希望的结果。此外,抗病毒药物,如替可韦和西多福韦降低发病率和死亡率。为了创造有针对性的治疗方法和改进治疗方案,进一步的研究是必要的。为了减轻猴痘对世界的影响,需要改进监测系统、公共卫生教育和国际合作。目前的研究通过对猴痘病毒流行率和现有治疗方法进行全面评估,强调了在疾病监测、预防和治疗改进方面开展持续工作的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Global monkeypox disease outbreak: Prevalence and treatment
Monkeypox is a zoonotic disease and caused by the monkeypox virus (MPXV). It belongs to the species of the orthopoxvirus family. Data from several sources, including epidemiological studies, case reports, and clinical trials were included in thorough literature analyses. Monkeypox was more common in Central and West Africa. Additionally, the virus has been identified in other regions of the world including North America, Europe, and Asia. A feverish sickness and distinctive skin lesions, resembling smallpox, are the primary symptoms of the disease. Preventing serious consequences and secondary transmission requires early diagnosis and effective care. The main therapeutic strategies used include vaccination, antiviral medication, and supportive care. Despite not being created expressly for monkeypox, the smallpox vaccination has shown some promising results in reducing serious illness. Additionally, antiviral medications such as tecovirimat and cidofovir lower the morbidity and mortality. To create targeted treatments and improve treatment plans, further research is necessary. In order to lessen the impact of monkeypox on the world, improved monitoring systems, public health education, and international cooperation are required. The current study highlights the necessity for ongoing work in disease monitoring, prevention, and therapeutic improvements by providing a thorough assessment of monkeypox viral prevalence and available treatments.
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