结膜黑色素瘤复发的预测因素

Agus Supartoto, M. Djaja, Datu Respatika, M. B. Sasongko
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引用次数: 0

摘要

结膜黑色素瘤可能致命的肿瘤。虽然许多结膜黑色素瘤的病例似乎是复发,但没有有效的数据参数来预测这种肿瘤的复发。本研究旨在评估组织病理学特征是否可以作为结膜黑色素瘤复发的预测因子。这是一项回顾性研究,涉及2013- 2010年在日惹的Dr. Sardjito总医院和Dr. Yap眼科医院的结膜黑色素瘤患者。患者的特征由年龄、性别、侧边、肿瘤大小、肿瘤位置、组织病理学优势、MMC应用、复发和转移决定。16例,男占62.5%,女占37.5%。年龄5 ~ 79岁,平均56.19岁。肿瘤位于球茎11例(68.7%),眼睑5例(31.3%)。转移与肿瘤复发有显著相关性(OR 13.0;95% ci 1.9-85.4;P = 0.007)。位置与黑色素瘤复发之间也有良好的关联趋势(OR 15.0;95% ci 0.9-228.8;P = 0.06)。总之,我们的研究表明发生远处转移的患者肿瘤复发的风险更大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The predictive factor for conjunctival melanoma recurrence
Conjunctival melanoma potentially deadly tumor. While many cases of conjunctival melanoma appeared to be a recurrence, there is no valid data about parameters to predict the recurrence of this tumor. This study intended to evaluate whether histopathologic features can be used as a predictor for recurrence in conjunctival melanoma. This was a retrospective study, involving patients with conjunctival melanoma by the year 2013-1017 in Dr. Sardjito General Hospital and Dr. Yap Eye Hospital, Yogyakarta. Patient’s characteristic was determined by age, sex, laterality, tumor size, tumor location, histopathological dominancy, MMC application, recurrence, and metastases. Sixteen cases were found: male (62.5%) and female (37.5%). Age from 5-79 years, mean was 56.19 years. Tumor location was in bulbar in 11 patients (68.7%), palpebral in 5 patients (31.3%).There was significant association between metastasis and the tumor recurrence (OR 13.0; 95% CI 1.9-85.4; p = 0.007). A favorable trend of association was also found between location and the recurrence of melanoma (OR 15.0; 95% CI 0.9-228.8; p = 0.06). In summary, our study showed that the patients that developing distant metastasis were at a greater risk for tumor recurrence.
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