{"title":"测定大鼠体内各器官的胆固醇合成速率","authors":"T. Magot, F. Chevallier","doi":"10.1051/RND:19791012","DOIUrl":null,"url":null,"abstract":"A method to measure the absolute values of the rate of cholesterol synthesis in vivo in the organs of the rat has been described. Adult male rats were intravenously infused for 3.5, 6 and 10 h with sodium 1-4 (C)-acetate and the specific activity of expired C0 2 was recorded during the experiment. Sterol radioactivities were measured in plasma, lipoproteins and in various organs, the radioactivities in each organ being corrected for cholesterol transfer. The rate of cholesterol synthesis in the intact rat and in each organ","PeriodicalId":7885,"journal":{"name":"Annales De Biologie Animale Biochimie Biophysique","volume":"11 1","pages":"1757-1770"},"PeriodicalIF":0.0000,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":"{\"title\":\"Measurement of the rate of cholesterol synthesis in various organs of the rat in vivo\",\"authors\":\"T. Magot, F. Chevallier\",\"doi\":\"10.1051/RND:19791012\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A method to measure the absolute values of the rate of cholesterol synthesis in vivo in the organs of the rat has been described. Adult male rats were intravenously infused for 3.5, 6 and 10 h with sodium 1-4 (C)-acetate and the specific activity of expired C0 2 was recorded during the experiment. Sterol radioactivities were measured in plasma, lipoproteins and in various organs, the radioactivities in each organ being corrected for cholesterol transfer. The rate of cholesterol synthesis in the intact rat and in each organ\",\"PeriodicalId\":7885,\"journal\":{\"name\":\"Annales De Biologie Animale Biochimie Biophysique\",\"volume\":\"11 1\",\"pages\":\"1757-1770\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1979-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annales De Biologie Animale Biochimie Biophysique\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1051/RND:19791012\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annales De Biologie Animale Biochimie Biophysique","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1051/RND:19791012","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Measurement of the rate of cholesterol synthesis in various organs of the rat in vivo
A method to measure the absolute values of the rate of cholesterol synthesis in vivo in the organs of the rat has been described. Adult male rats were intravenously infused for 3.5, 6 and 10 h with sodium 1-4 (C)-acetate and the specific activity of expired C0 2 was recorded during the experiment. Sterol radioactivities were measured in plasma, lipoproteins and in various organs, the radioactivities in each organ being corrected for cholesterol transfer. The rate of cholesterol synthesis in the intact rat and in each organ
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