苏门答腊北方大学医院高血压患者药物相关问题与血压的关系

Mutiara Siahaan, A. Nasution, W. Wiryanto, I. Iksen
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引用次数: 1

摘要

高血压患者通常会出现慢性合并症和并发症,需要复杂的治疗(多种药物),这可能进一步导致药物相关问题(DRPs)并干扰所需的临床结果。本研究采用病例对照前瞻性横断面法,旨在分析2021年7月至9月入住Universitas sumata Utara (USU)医院的高血压患者DRPs与血压(bp)之间的关系。根据Cipolle分类系统和可靠文献对DRPs的发生率进行分析和分类。将患者的血压分为控制血压和不控制血压。采用卡方检验分析DRPs与BP之间的相关性。绝大多数患者为女性(57.5%)。平均年龄59±9.94岁。患者DRPs的平均发生率为1.78±0.79。最常见的drp是药物相互作用。患者经历的drp次数与其bp之间存在显著相关性(p=0.02)。DRPs是导致高血压患者血压失控的重要因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association between Drug-Related Problems and Blood Pressure of Hypertensive Patients Admitted to Universitas Sumatera Utara Hospital
Patients with hypertension usually experience chronic comorbidities and complications that require complex treatment (polypharmacy), which can further cause drug-related problems (DRPs) and interfere with the required clinical outcomes. This study, by using a case-control prospective cross-sectional, aimed to analyze the association between DRPs and blood pressures (BPs) of hypertensive patients admitted to Universitas Sumatera Utara (USU) hospital from July to September 2021. The incidence of DRPs was analyzed and classified according to the Cipolle classification system and reliable literature. Blood pressures of the patients were classified into controlled and uncontrolled BPs. The association between DRPs and BP was analyzed using the Chi-Square test. Most of the patients (57.5%) were female. Their mean age was 59±9.94 (years). The mean incidence of DRPs experienced by the patients was 1.78±0.79. The most frequently occurred DRPs were drug interactions. There was a significant association between the number of DRPs experienced by the patients and their BPs (p=0.02). DRPs are the contributing factor to the uncontrolled BPs of hypertensive patients.
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