Compliance for Oral Antidiabetic Agents and its Improvement by One dose Package.

The compliance of 60 year old or older diabetic patients taking oral antidiabetic agents was investigated. As a result, the compliance for oral antidiabetic agents with different dosing times declined according to the frequency that such medicine had to be taken.It is suggested that this case occurs when the complexity of medicines increases by using a heat seal and when patient's concern to oral antidiabetic agents declines since packaging forms of medicines are the same. A good compliance was obtained regardless of the dosing time if the total number of medications were 4 or less, if all the medicines could be included in one dose package and if the dosing time for all medicines was the same.