蜂蜜加蜂蜜可改善雄性白化病小鼠的一些血液学指标

N. Igbokwe, I. Kashim, Short Communication
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引用次数: 0

摘要

研究了蜂蜜和啤酒面包对15只明显健康的成年白化病雄性小鼠血液参数的影响。在两周的适应期后,这些小鼠被分成三组,每组5只。A组小鼠口服蒸馏水作为对照,B组和C组小鼠分别灌胃蜂蜜和啤酒面包,剂量率为1g/kg体重,浓度为40% w/v,以水为载体,每天1次,连续70 d。微红细胞压积法和血细胞计数法分别用于测定堆积细胞体积和红细胞计数和白细胞计数。用氰高铁血红蛋白法测定血红蛋白浓度。与对照组相比,治疗组的红细胞计数、堆积细胞体积和血红蛋白浓度显著增加(p小于0.05),其中以食用啤酒面包组的增幅最大。处理组的白细胞总数显著增加(p小于0.05),其中蜂蜜处理组记录的白细胞总数最高。各治疗组淋巴细胞和中性粒细胞显著升高(p小于0.05),但嗜酸性粒细胞、嗜碱性粒细胞和单核细胞数量无显著变化(p > 0.05)。本研究证实了添加蜂蜜和蜂蜜面包的饲料具有积极的造血作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Beebread and Honey improves some Haematologic Parameters in Male ‎Albino Mice
The effects of honey and beebread on some haematological parameters were investigated in fifteen apparently healthy adult albino male mice. The mice were divided into three groups of five mice each after a two-week period of acclimatization. The mice in group A were given distilled water orally to serve as a control while those in groups B and C were administered honey and beebread respectively by gavages at the dose rate of 1g/kg body weight and at a concentration of 40% w/v using water as a vehicle, once daily for 70 consecutive days. Micro-haematocrit and hematocytometry were used for determination of packed cell volume and erythrocyte and differential leucocyte counts, respectively. Haemoglobin concentration was estimated by using Cyanmethemoglobin method. There were significant (p ˂0.05) increases in the red blood cells count, packed cell volume and haemoglobin concentration in the treatment groups compared to the control group, with the most increase observed in the group treated with beebread. There was significant (p ˂ 0.05) increase in total leucocyte count in the treated groups with the highest count recorded in the honey treated group than the control. Lymphocytes and neutrophils significantly (p ˂ 0.05) increased in the treatment groups but there were no significant (P > 0.05) changes in the number of eosinophils, basophils and monocytes. The study demonstrates the positive haematopoietic effects of supplementation of feed with honey and beebread.  
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