查尔酮及其金属配合物的化学和生物活性研究进展

Thakor Shivani R, Sharma Bhavesh R
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引用次数: 3

摘要

查尔酮是一种芳香的酮,它为各种重要的有机混合物构建了一个焦点中心,这些混合物统称为查尔酮。它们具有抗菌、抗真菌、缓解和抗肿瘤等多种功效,依赖于它们的替代品。查尔酮是类黄酮家族中占有一席之地的常规物质。查尔酮是1,3 -二苯基-2-丙烯-1- 1,其中两个芳香环由三碳α, β-不饱和羰基框架连接。查尔酮和他们的杂环类似物欣赏有机运动的范围,例如,抗菌剂,癌症预防剂,细胞毒性,抗癌,抗原虫,抗组胺剂,抗溃疡和镇静运动,这使得这些混合物作为一个非凡的魅力检查。两个环之间的亲双电酮基链具有很强的接受性,作为一个重要的合成物,可以构建不同的五,六,七部分杂环框架,包含不同的杂分子,如氮,氧和硫,通过压缩的形式与各种亲双核试剂结合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A review: Chemical and biological activity of chalcones with their metal complex
Chalcone is a fragrant ketone that frames a focal center for an assortment of significant organic mixes, which are altogether known as chalcones. They have various exercises like antibacterial, antifungal, mitigating and against tumor and so on relying upon the replacement made on them. Chalcones are regular item has a place with Flavonoid family. Chalcones are 1, 3-diphenyl-2-propene-1-one, in which two fragrant rings are connected by a three carbon α, β-unsaturated carbonyl framework. Chalcones and their heterocyclic analogs appreciate a scope of organic exercises, for example, antimicrobial, cancer prevention agent, cytotoxic, anticancer, antiprotozoal, antihistaminic, antiulcer and calming exercises which makes these mixes as an extraordinary fascination for examination. Also the bielectrophilic, ketovinyl chain between the two rings is profoundly receptive and goes about as a significant synthetic synthon for building diverse five, six and seven part heterocyclic frameworks containing distinctive hetero molecules like nitrogen, oxygen and sulfur iotas by compressed version with an assortment of binucleophilic reagents.
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