胡芦巴-葫芦巴种子提取物的植物成分分析

IF 0.5 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Studia Universitatis Babes-bolyai Chemia Pub Date : 2017-01-01 DOI:10.24193/SUBBCHEM.2017.2.11

Szabolcs Vígh, Z. Cziáky, L. Sinka, C. Pribac, L. Moș, V. Turcuș, J. Remenyik, E. Máthé

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引用次数: 5

摘要

葫芦巴(Trigonella foenum-graecum L.)是一种众所周知的草药，它在预防/治疗糖尿病和其他慢性疾病方面效率很高。本研究的目的是分析在匈牙利生产的胡芦巴种子的水和水醇提取物的植物成分。采用UHPLC-ESI-MS方法对水提取物和水水提取物进行了分析，在前54种提取物中鉴定出67种植物成分，而在第二种提取物中鉴定出的植物成分大多证实了先前描述的胡芦巴促进健康的作用。然而，将这两种提取物的植物成分与我们报道的在某些人乳腺癌细胞系中产生的剂量依赖性辐射反应和细胞毒性作用联系起来仍然是一个巨大的挑战。

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Analysis of phytoconstituent profile of fenugreek –Trigonella Foenuem-graecum L. - seed extracts

Fenugreek (Trigonella foenum-graecum L.) is a well-known herb for its efficiency in the prevention/treatment of diabetes among other chronic diseases. The aim of present study was to analyse the phytoconstituent profile of aqueous and hydro-alcoholic extracts of fenugreek seeds produced in Hungary. The aqueous and hydro-aqueous extracts were analysed using a UHPLC-ESI-MS approach, and in the first 54, while in the second extract 67 phytoconstituents were identified that mostly corroborate the previously described health promoting effects of fenugreek. However, it remains a huge challenge to correlate the phytoconstituent composition of the two extracts with the generated dose dependent hormetic response and cytotoxic effects that were reported by us in case of some human breast cancerous cell lines.

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来源期刊

Studia Universitatis Babes-bolyai Chemia 化学-化学综合

CiteScore

0.80

自引率

33.30%

发文量

审稿时长

>12 weeks

期刊介绍： Studia Universitatis Babes-Bolyai, Seria Chemia publishes fundamental studies in all areas of chemistry and chemical engineering. Coverage includes experimental and theoretical reports on quantitative studies of structure and thermodynamics, kinetics, mechanisms of reactions, inorganic, organic, organometallic chemistry, biochemistry, computational chemistry, solid-state phenomena, surface chemistry, chemical technology and environmental chemistry.