一种基于模型的自主神经活动和灵敏度测量方法

Proceedings of the 2019 6th International Conference on Biomedical and Bioinformatics Engineering Pub Date : 2019-11-13 DOI:10.1145/3375923.3375944

Xiang'ao Meng, Zhipei Huang, Jiankang Wu

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引用次数: 1

摘要

自主神经活动的测量在各种心血管疾病的诊断和治疗中起着重要作用。本文提出了一种基于模型的测量自主神经活动和灵敏度的方法。通过无创记录受试者在坐立实验过程中的心率和血压数据，建立血压-心率调节系统模型，求解个性化参数。这些个性化参数用于获得受试者的自主神经活动和灵敏度。我们对9名难治性高血压患者和20名健康人进行了实验，结果显示自主神经的敏感性和活动性有显著差异。

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A Model-based Method for Measuring Autonomic Nerve Activity and Sensitivity

The measurement of autonomic nerve activity plays an important role in the diagnosis and treatment of various cardiovascular diseases. This paper presents a model-based method for measuring autonomic nerve activity and sensitivity. By non-invasively recording heart rate and blood pressure data of the subjects during the sit-to-stand experiment, we modeled the blood pressure-heart rate regulation system and solved personalized parameters. These personalized parameters were used to obtain the autonomic nerve activity and sensitivity of the subjects. We conducted experiments on 9 patients with refractory hypertension and 20 healthy people, and the results showed that there were significant differences in the sensitivity and activity of autonomic nerves.

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Proceedings of the 2019 6th International Conference on Biomedical and Bioinformatics Engineering

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