{"title":"一种基于模型的自主神经活动和灵敏度测量方法","authors":"Xiang'ao Meng, Zhipei Huang, Jiankang Wu","doi":"10.1145/3375923.3375944","DOIUrl":null,"url":null,"abstract":"The measurement of autonomic nerve activity plays an important role in the diagnosis and treatment of various cardiovascular diseases. This paper presents a model-based method for measuring autonomic nerve activity and sensitivity. By non-invasively recording heart rate and blood pressure data of the subjects during the sit-to-stand experiment, we modeled the blood pressure-heart rate regulation system and solved personalized parameters. These personalized parameters were used to obtain the autonomic nerve activity and sensitivity of the subjects. We conducted experiments on 9 patients with refractory hypertension and 20 healthy people, and the results showed that there were significant differences in the sensitivity and activity of autonomic nerves.","PeriodicalId":20457,"journal":{"name":"Proceedings of the 2019 6th International Conference on Biomedical and Bioinformatics Engineering","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A Model-based Method for Measuring Autonomic Nerve Activity and Sensitivity\",\"authors\":\"Xiang'ao Meng, Zhipei Huang, Jiankang Wu\",\"doi\":\"10.1145/3375923.3375944\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The measurement of autonomic nerve activity plays an important role in the diagnosis and treatment of various cardiovascular diseases. This paper presents a model-based method for measuring autonomic nerve activity and sensitivity. By non-invasively recording heart rate and blood pressure data of the subjects during the sit-to-stand experiment, we modeled the blood pressure-heart rate regulation system and solved personalized parameters. These personalized parameters were used to obtain the autonomic nerve activity and sensitivity of the subjects. We conducted experiments on 9 patients with refractory hypertension and 20 healthy people, and the results showed that there were significant differences in the sensitivity and activity of autonomic nerves.\",\"PeriodicalId\":20457,\"journal\":{\"name\":\"Proceedings of the 2019 6th International Conference on Biomedical and Bioinformatics Engineering\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 2019 6th International Conference on Biomedical and Bioinformatics Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1145/3375923.3375944\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 2019 6th International Conference on Biomedical and Bioinformatics Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1145/3375923.3375944","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Model-based Method for Measuring Autonomic Nerve Activity and Sensitivity
The measurement of autonomic nerve activity plays an important role in the diagnosis and treatment of various cardiovascular diseases. This paper presents a model-based method for measuring autonomic nerve activity and sensitivity. By non-invasively recording heart rate and blood pressure data of the subjects during the sit-to-stand experiment, we modeled the blood pressure-heart rate regulation system and solved personalized parameters. These personalized parameters were used to obtain the autonomic nerve activity and sensitivity of the subjects. We conducted experiments on 9 patients with refractory hypertension and 20 healthy people, and the results showed that there were significant differences in the sensitivity and activity of autonomic nerves.