番茄果实提取物:一种合成异恶唑衍生物的环保型催化介质

IF 0.5 4区 化学 Q3 Pharmacology, Toxicology and Pharmaceutics
B. Popatkar, Ankita A Mane, G. Meshram
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引用次数: 1

摘要

以番茄果实提取物为催化介质,采用芳香醛、盐酸羟胺和乙酸乙酯/乙酸甲酯一锅多组分反应合成了异恶唑类化合物。发现番茄果实提取物是合成标题化合物的良好催化介质。该方法具有反应条件温和、易于分离、产率中高、反应时间短等优点,较已有报道的合成异恶唑衍生物的方法更具吸引力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tomato fruit extract: an environmentally benign catalytic medium for the synthesis of isoxazoles derivatives
One-pot multicomponent reaction between aromatic aldehyde, hydroxylamine hydrochloride and ethyl acetoacetate/ methyl acetoacetate for the synthesis of isoxazoles derivatives by employing tomato fruit extract as a catalytic medium has been developed. Tomato fruit extract was found to be a favorable catalytic medium for the synthesis of titled compounds. Mild reaction condition, ease of separation, moderate to high yield of the product, and short reaction time makes this method more attractive over earlier reported methods for the synthesis of isoxazoles derivatives.
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来源期刊
自引率
0.00%
发文量
1
审稿时长
4-8 weeks
期刊介绍: Indian Journal of Chemistry (Section B) is a leading monthly journal in Organic and Medicinal Chemistry started publishing from 1976. It publishes papers on organic reaction mechanism, theoretical organic chemistry, structure-activity relationships, medicinal chemistry, synthesis of chiral compounds, bio-organic chemistry, enzymes in organic synthesis, reagents in organic synthesis, heterocyclic compounds, phytochemistry (natural products), amino acids, peptides and proteins, spectroscopy in characterization of organic compounds, chemoenzymatic and enantioselective synthesis of organic compounds, synthesis of fullerenes, metal-catalyzed asymmetric reactions, bioactive plant products and combinatorial chemistry. Apart from full length papers, notes and communications, the journal publishes short reviews on frontline areas under the column " advances in Contemporary Research".
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