与新冠肺炎相关的糖尿病病例系列随访:β细胞损伤能否恢复?

Pub Date : 2023-01-01 DOI:10.26497/cc220052

M. Stumpf, L. Lins, Priscilla Cukier, M. Nery, M. Giannella, M. E. Rossi da Silva

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引用次数: 0

摘要

SARS-CoV-2感染可能与新发糖尿病和糖尿病酮症酸中毒(DKA)有关。我们描述了在急诊科出现的3例DKA和COVID-19的长期随访。其中2例患者的临床过程允许在随访期间停止胰岛素治疗。第三个病例，一个更严重的肺血栓栓塞，在随访期间继续需要睡前胰岛素。这些病例表明，胰岛素治疗可以控制糖毒性，并帮助β细胞在COVID-19等急性损伤后恢复。

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A CASE SERIES OF FOLLOW-UPS IN COVID-RELATED DIABETES: COULD THE DAMAGE IN BETA CELLS BE RECOVERED?

SARS-CoV-2 infection may be related to new-onset diabetes and diabetic ketoacidosis (DKA). We describe a long-term follow-up of 3 cases presented in the Emergency Department with DKA and COVID-19. In 2 of them, the clinical course permitted withdrawal of insulin therapy during follow-up. The third case, a more serious one with pulmonary thromboembolism, continued to require bedtime insulin during the follow-up period. Such cases demonstrate that insulin treatment can control glucotoxicity and help beta cells recover after an acute insult such as COVID-19.

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