Anju Mullath, A. Koshy, Roy j. Mukkada, A. Chettupuzha, S. Paul, P. Mathew, P. Mahadevan, Murali Krishna
{"title":"Lynch综合征的胆道内结直肠转移:指数癌后15年","authors":"Anju Mullath, A. Koshy, Roy j. Mukkada, A. Chettupuzha, S. Paul, P. Mathew, P. Mahadevan, Murali Krishna","doi":"10.7869/TG.590","DOIUrl":null,"url":null,"abstract":"Tropical Gastroenterology 96 The duration of antifungal treatment is guided by the resolution of clinical and radiological features which may take 6 to 8 weeks. The recommended therapeutic drug level of posaconazole is a trough concentration of 1 μg/mL or higher4. Delayed presentation with inability to remove the infected intestinal segment and use of parenteral antifungal therapy alone in an immunocompromised patient might have led to fatality in our case. Therefore, a high degree of clinical suspicion, early diagnosis and prompt surgical debridement with anti -fungal therapy might improve survival.","PeriodicalId":23281,"journal":{"name":"Tropical gastroenterology : official journal of the Digestive Diseases Foundation","volume":"118 1","pages":"96-99"},"PeriodicalIF":0.0000,"publicationDate":"2020-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Intra-Biliary Colorectal Metastasis in Lynch Syndrome: Fifteen Years After the Index Cancer\",\"authors\":\"Anju Mullath, A. Koshy, Roy j. Mukkada, A. Chettupuzha, S. Paul, P. Mathew, P. Mahadevan, Murali Krishna\",\"doi\":\"10.7869/TG.590\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tropical Gastroenterology 96 The duration of antifungal treatment is guided by the resolution of clinical and radiological features which may take 6 to 8 weeks. The recommended therapeutic drug level of posaconazole is a trough concentration of 1 μg/mL or higher4. Delayed presentation with inability to remove the infected intestinal segment and use of parenteral antifungal therapy alone in an immunocompromised patient might have led to fatality in our case. Therefore, a high degree of clinical suspicion, early diagnosis and prompt surgical debridement with anti -fungal therapy might improve survival.\",\"PeriodicalId\":23281,\"journal\":{\"name\":\"Tropical gastroenterology : official journal of the Digestive Diseases Foundation\",\"volume\":\"118 1\",\"pages\":\"96-99\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tropical gastroenterology : official journal of the Digestive Diseases Foundation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7869/TG.590\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tropical gastroenterology : official journal of the Digestive Diseases Foundation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7869/TG.590","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Intra-Biliary Colorectal Metastasis in Lynch Syndrome: Fifteen Years After the Index Cancer
Tropical Gastroenterology 96 The duration of antifungal treatment is guided by the resolution of clinical and radiological features which may take 6 to 8 weeks. The recommended therapeutic drug level of posaconazole is a trough concentration of 1 μg/mL or higher4. Delayed presentation with inability to remove the infected intestinal segment and use of parenteral antifungal therapy alone in an immunocompromised patient might have led to fatality in our case. Therefore, a high degree of clinical suspicion, early diagnosis and prompt surgical debridement with anti -fungal therapy might improve survival.