α -亚麻酸:一种天然药理活性成分

Devika Srivastava, Vandana Singh, U. Kumar, V. R.
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引用次数: 1

摘要

α -亚麻酸(ALA)是一种必需的omega - 3脂肪酸,主要存在于植物中。由于这个原因,ALA不能在人体内合成,它应该包括在饮食中的各种来源,如亚麻籽,核桃,菜籽油等。ALA是其他omega - 3脂肪酸的前体,即二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)。这两种脂肪酸来源于动物,并被证明对健康有很多好处。此外,多项研究已明显支持ALA具有神经保护、心脏保护、抗炎、抗癌、肝保护、抗氧化和抗糖尿病等药理作用。ALA的有益作用可归因于其生物利用度几乎与其他脂肪酸一样完全。本文综述了ALA的药理作用及其生物利用度和代谢的相关文献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Alpha-Linolenic acid: A Pharmacologically Active Ingredient from Nature
Alpha-linolenic acid (ALA) is an essential omega 3 fatty acid which is mostly found in plants. ALA is not synthesized in the human body due to this reason, it should be included in diet from various sources such as flaxseed, walnut, canola oil etc. ALA is a precursor of other omega 3 fatty acids namely Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA). These two fatty acids are derived from animal sources and are documented with many health benefits. Further, various studies have evidently supported the pharmacological activities of ALA such as neuroprotective, cardioprotective, anti-inflammatory, anticancer, hepatoprotective, antioxidant and anti-diabetic. The beneficial effects of ALA can be attributed due to its bioavailability which is almost complete like other fatty acids. This review covers the pharmacological actions of ALA and its bioavailability and metabolism with the help of available literature under one roof.
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