肉桂提取物和蜂蜜对烧伤单位多药铜绿假单胞菌增效作用的评价

Q3 Medicine

Reviews in Medical Microbiology Pub Date : 2020-04-01 DOI:10.1097/MRM.0000000000000202

Pezhman Karami, A. Khaledi, D. Dastan, M. Yaghoobi, M. Karami, Rasool Yousefi Mashoof, M. Alikhani

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引用次数: 0

摘要

方法:根据临床与实验室标准协会(CLSI)的指南，采用微量肉汤稀释法测定每种抗生素(庆大霉素和环丙沙星)单独使用或与肉桂和蜂蜜的水提物和醇提物联合使用时铜绿假单胞菌临床和环境分离株的最低抑菌浓度(MIC)和最低杀菌浓度(MBC)。采用棋盘格法评价组合的协同效应。数据分析采用卡方检验和Fisher精确检验(SPSS软件)。p值小于0.05认为差异有统计学意义。

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Evaluation of the synergistic effect of cinnamon extract and honey against multidrug-resistant isolates of Pseudomonas aeruginosa recovered from burn unit

Methods: The minimum inhibitory concentration (MIC) and minimum bactericidal concentrations (MBC) of each antibiotic (Gentamicin and Ciprofloxacin) alone or in combination with the aqueous and alcoholic extracts of cinnamon and honey was determined by broth microdilution method for clinical and environmental isolates of P. aeruginosa based on the Clinical & Laboratory Standards Institute (CLSI) guidelines. The synergisticeffectof combinations was evaluatedusing a checkerboard test.Data analyzed using chi-square and Fisher’s exact tests (SPSS software). P-value of less than 0.05 was considered to indicate statistically significant differences.

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来源期刊

Reviews in Medical Microbiology 生物-微生物学

CiteScore

1.80

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Reviews in Medical Microbiology is a quarterly review journal which provides a balanced coverage of the whole field of medical microbiology. The Journal publishes state-of-the art reviews, mini-reviews, case presentations and original research from on-going research of the latest developments and techniques in medical microbiology, virology, mycology, parasitology, clinical microbiology, and hospital infection. In addition, PhD-Review - a platform for young researchers, and biographical Bio-Sketch articles are also considered. Reviews are concise, authoritative, and readable synthesis of the latest information on its subject, and references are limited to the fifty key sources for full reviews and twenty for mini-reviews. Reviews in Medical Microbiology is the perfect way for both qualified and trainee microbiologists, and researchers and clinicians with an interest in microbiology, to stay fully informed of the latest developments in medical microbiology. The journal is a valuable resource for educational and teaching purposes.