一种药用生物技术产品,用钩形皂(Clitoria ternatea L)作为一种抗真菌的念珠菌

A. Ma'ruf, E. Safitri, Fernanda Desmak Pertiwi, Retna Yulrosly Ningtias, D. Trisnawati, Firman Rezaldi, K. Kusumiyati, Poniyah Andayaningsih
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引用次数: 6

摘要

特朗花康普茶除了作为一种益生菌饮料在食品领域发挥重要作用外,在制药(化妆品)领域,特别是在制备益生菌液浴皂方面具有抑制白色念珠菌生长的潜力,白色念珠菌会导致女性阴道分泌物。本研究以发酵康普茶特朗花液为有效成分,分别在20%、30%和40%浓度下抑制白色念珠菌生长,制备益生菌液浴皂的配方和制剂。本研究方法为室内实验,以发酵康普茶特朗花液为有效成分,分别以浓度为20%、30%、40%和皂基为阴性对照,以市场上可买到的生物皂为阳性对照,制备4种益生菌液浴皂制剂。圆盘扩散法检测白色念珠菌的生长抑制作用。数据分析采用单因素方差分析进行统计,进一步检验采用事后分析的形式进行。本研究结果表明,康普茶花特朗沐浴皂的最佳抑菌浓度为40%,抑菌带平均直径为20.52 mm。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PRODUK BIOTEKNOLOGI FARMASI BERUPA SABUN MANDI KOMBUCHA BUNGA TELANG (Clitoria ternatea L) SEBAGAI ANTIFUNGI Candida albicans
Telang flower kombucha besides playing an important role in the food sector as a probiotic drink, it has potential in the pharmaceutical (cosmetic) field, especially in the preparation of probiotic liquid bath soap in inhibiting the growth of Candida albicans which causes vaginal discharge in the female intimate organs. This study aims to make formulations and preparations of probiotic liquid bath soap with active ingredients from fermented kombucha telang flower solution at concentrations of 20%, 30%, and 40% in inhibiting the growth of Candida albicans. This research method is a laboratory experiment by making 4 preparations of probiotic liquid bath soap with active ingredients from fermented kombucha telang flower solution at concentrations of 20%, 30%, 40%, and soap base as a negative control and the use of biore soap available in the market as a positive control. Testing on the growth inhibition of Candida albicans using the disc diffusion method. Data analysis was carried out statistically using one-way ANOVA and further tests were carried out in the form of post hoc analysis. The conclusion in this study was that the concentration of 40% in the preparation of kombucha flower telang bath soap was the best concentration as antifungal Candida albicans with an average diameter of the resulting inhibition zone was 20.52 mm.
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