Mohammad Abdollahi Ahmadreza Dehpour Golriz Baharnouri
{"title":"铷对大鼠颌下腺分泌功能的影响","authors":"Mohammad Abdollahi Ahmadreza Dehpour Golriz Baharnouri","doi":"10.1080/107691898229369","DOIUrl":null,"url":null,"abstract":"Effects of rubidium chloride (1200 mg/L drinking water) treatment for 10 d on rat submandibular saliva composition were examined in this study. Both submandibular ducts were cannulated intraorally with polyethylene tubes, and pure saliva was collected from anesthetized rubidium-treated and control rats using pilocarpine as a secretagogue. Saliva protein and calcium concentrations were found to be significantly (p < .05) increased in rubidium-treated groups. N -acetyl-beta-D-glucosaminidase (NAG) is one of the sensitive hydrolytic lysosomal enzymes that can be released after submandibular gland damage. The secretion of NAG in saliva increased significantly ( p <.01)after rubidium treatment. Salivary flow rate, normalized for gland weight, was also affected by rubidium treatment as there was a significant (p <.01) reduction of flow rate in rubidium-exposed rats. There is no obvious basis for these alterations in saliva protein and calcium content and in flow rate induced with rubidium, but possible...","PeriodicalId":87425,"journal":{"name":"Toxic substance mechanisms","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"24","resultStr":"{\"title\":\"EFFECTS OF RUBIDIUM ON THE SECRETORY FUNCTION OF THE RAT SUBMANDIBULAR GLAND\",\"authors\":\"Mohammad Abdollahi Ahmadreza Dehpour Golriz Baharnouri\",\"doi\":\"10.1080/107691898229369\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Effects of rubidium chloride (1200 mg/L drinking water) treatment for 10 d on rat submandibular saliva composition were examined in this study. Both submandibular ducts were cannulated intraorally with polyethylene tubes, and pure saliva was collected from anesthetized rubidium-treated and control rats using pilocarpine as a secretagogue. Saliva protein and calcium concentrations were found to be significantly (p < .05) increased in rubidium-treated groups. N -acetyl-beta-D-glucosaminidase (NAG) is one of the sensitive hydrolytic lysosomal enzymes that can be released after submandibular gland damage. The secretion of NAG in saliva increased significantly ( p <.01)after rubidium treatment. Salivary flow rate, normalized for gland weight, was also affected by rubidium treatment as there was a significant (p <.01) reduction of flow rate in rubidium-exposed rats. There is no obvious basis for these alterations in saliva protein and calcium content and in flow rate induced with rubidium, but possible...\",\"PeriodicalId\":87425,\"journal\":{\"name\":\"Toxic substance mechanisms\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1998-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"24\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Toxic substance mechanisms\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/107691898229369\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxic substance mechanisms","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/107691898229369","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
EFFECTS OF RUBIDIUM ON THE SECRETORY FUNCTION OF THE RAT SUBMANDIBULAR GLAND
Effects of rubidium chloride (1200 mg/L drinking water) treatment for 10 d on rat submandibular saliva composition were examined in this study. Both submandibular ducts were cannulated intraorally with polyethylene tubes, and pure saliva was collected from anesthetized rubidium-treated and control rats using pilocarpine as a secretagogue. Saliva protein and calcium concentrations were found to be significantly (p < .05) increased in rubidium-treated groups. N -acetyl-beta-D-glucosaminidase (NAG) is one of the sensitive hydrolytic lysosomal enzymes that can be released after submandibular gland damage. The secretion of NAG in saliva increased significantly ( p <.01)after rubidium treatment. Salivary flow rate, normalized for gland weight, was also affected by rubidium treatment as there was a significant (p <.01) reduction of flow rate in rubidium-exposed rats. There is no obvious basis for these alterations in saliva protein and calcium content and in flow rate induced with rubidium, but possible...
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