Report of Comprehensive Periodontal Treatment of a Case of Severe Drug-induced Gingival Overgrowth with Malaligned Teeth

: Gingival hyperplasia is well known to occur as an adverse effect of antihypertensive drugs, anticonvulsants, and immunosuppressants. Herein, we report a case of comprehensive periodontal treatment in a patient with severe drug-induced gingival hyperplasia accompanied by malaligned teeth and occlusion collapse caused by intake of a Ca-channel blocker (as an antihypertensive) for over 10 years, in which marked improvement of the periodontal condition was confirmed. Changing the antihypertensive drug (Ca-channel blocker) was not possible because the drug proved essential for good control of the blood pressure, but the supportive periodontal therapy was able to prevent recurrence. The periodontal condition has been well maintained post treatment.