聚乙烯醇-壳聚糖互穿网络的溶胀行为及药物释放

F. S. Matty, Zainab Mohialdeen
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引用次数: 2

摘要

聚乙烯醇和壳聚糖可生物降解,无毒,生物相容性聚合物,方便用于药物释放。本文研究了聚乙烯醇(PVA)和壳聚糖(CS)水凝胶与戊二醛(GA)交联的不同比例形态和结构表征互穿聚合物网络(IPN)。采用傅里叶透射红外光谱(FTIR)、扫描电镜(SEM)、紫外可见分光光度计对其进行了表征,并通过改变交联比和PH对水凝胶的溶胀和药物释放进行了研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Swelling Behavior and Drug Release of Interpenetrating Network Composed of PVA and Chitosan
PVA and chitosan biodegradable, non-toxic, biocompatible polymers convenient for use in drug release. In this study polyvinyl alcohol (PVA) and chitosan (CS) hydrogels crosslinked with glutaraldehyde (GA) with different ratio morphology and structure characterization interpenetrating polymer network (IPN).They were investigated by Fourier transmission infrared spectroscopy (FTIR), scanning electron microscope (SEM), UV-Visible spectrophotometer,swelling of hydrogel and drug release were studied by changing crosslinking ratio and PH.
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