BIOCHEMICAL EVALUATION AND SCIENTIFIC VALIDATION STUDIES OF AN HERBAL NUTRACEUTICAL (IN PRESS)

The search for pioneering nutraceuticals from plants is genuine and crucial. Based on the literature review as per Ayurvedic texts, four common plants Capparis spinosa L. (flower buds), Caesalpinia bonducella  L.(seeds),  Luffa acutangula L.(fruits) and Cassia occidentalis L. (aerial parts) were selected to develop nutraceuticals and were standardized. Based on the nutraceutical and pharmacological efficacies of the individual plant drugs selected, three different herbal nutraceutical formulations were prepared. Nutraceuticals before and after lyophilization were subjected to standardization studies. Nutraceutical formulation 3 developed was found to be best due to its high nutraceutical values when compared to others. Results depicted that up to the dose level of 2000 mg/kg.bw (acute oral toxicity), 1000 mg/kg.bw (sub-acute oral toxicity), it doesn’t produced any lethality in the experimental animals. To conclude that the selected herbal formulation developed from selected plant ingredients was found to possess distinct nutraceutical values. The present work contributes for the development of human healthcare through nutraceutical product with remarkable medicinal properties in herbal way.