用scheimpflug相机评价角膜胶原交联治疗圆锥角膜后角膜地形图指标的变化

Amr Alamin, Adel Khalil, H. El-Rahman
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引用次数: 1

摘要

圆锥角膜是一种双侧角膜进行性扩张,导致不规则散光和近视。我们可以使用眼镜或隐形眼镜来矫正圆锥角膜的症状,而在晚期病例中,角膜移植是唯一的治疗方法。角膜胶原交联(CXL)是一种很有前途的治疗圆锥角膜的方法。目的评价圆锥角膜患者角膜CXL术后角膜地形图指标的变化,并分析这些变化。患者和方法对圆锥角膜行CXL手术。采用Pentacam地形仪测量角膜地形图的定量描述符,包括表面方差指数、垂直不对称指数、圆锥角膜指数、中心圆锥角膜指数、最小曲率半径、高度不对称指数和高度分散指数7个指标。随访6个月。结果本研究纳入35例圆锥角膜患者50只眼。在整个患者队列中,与基线相比,6个月时角膜表面方差指数、垂直不对称指数、圆锥角膜指数和最小曲率半径均有显著改善(均P<0.001)。结论CXL术后6个月,7项地形图指标中有4项有所改善,角膜形态整体改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Changes of corneal topography indices after corneal collagen crosslinking for treatment of keratoconus assessed by scheimpflug camera
Introduction Keratoconus is a bilateral, progressive ectasia of the cornea resulting in irregular astigmatism and myopia. We can use spectacles or contact lenses to correct the symptoms of keratoconus, whereas in advanced cases, corneal grafting is the only treatment. Corneal collagen cross-linking (CXL) is a promising treatment to strengthen and stabilize the cornea in cases of keratoconus. Aim To evaluate changes in corneal topography indices after corneal CXL in patients with keratoconus and analyze these changes. Patient and methods CXL was performed in eyes with keratoconus. Quantitative descriptors of corneal topography were measured with the Pentacam topographer and included seven indices: index of surface variance, index of vertical asymmetry, keratoconus index, central keratoconus index, minimum radius of curvature, index of height asymmetry, and index of height decentration. Follow-up was 6 months. Results The study comprised 50 eyes of 35 patients with keratoconus. In the entire patient cohort, there were significant improvements in the index of surface variance, index of vertical asymmetry, keratoconus index, and minimum radius of curvature at 6 months compared with baseline (all P<0.001). Conclusion There were improvements in four of seven topography indices 6 months after CXL, suggesting an overall improvement in corneal shape.
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