大黄在血癌化疗后患者中的应用及临床观察

Dr. Rameshwar Mahaseth, Dr. Sidhi Datri Jha, Dr. Digbijay Kumar Thakur
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引用次数: 0

摘要

目的:临床应用重组人促红细胞生成素(rHuEPO)可有效提高患者血中血红蛋白水平,改善患者生活质量。方法:将血癌患者分为治疗组和对照组。共有24例患者在gp治疗中同时给予化疗和rHuEPO 4周。rHuEPO按150u/kg剂量皮下注射,每周3次。每周做一次血常规检查,每两周开一次铁。结果:治疗4周后,对两组患者进行药物疗效评价;总有效率分别为58.34%和20%,P >0.05;治疗4周后,差异有统计学意义。与治疗前相比,治疗组4周后Hb显著升高(81.29±9.85)~(65.75±12.37),差异有统计学意义(P0.05)。结论:使用rHuEPO后Hb明显升高,副作用少,耐受性好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Application of Rhuepo to Post-Chemotherapy Blood Cancer Patients and Clinical Observation
Aim: Clinical use of Recombinant Human Erythropoietin (rHuEPO) effectively increases the level of Hemoglobin in blood and improve quality of life of patients. Methods: Blood cancer patients is divided into two groups namely Treatment group and Control group. There is altogether 24 patients in treatment gp to whom both chemotherapy and rHuEPO is given for 4 weeks. rHuEPO is given as 150u/kg,subcutaneously, three times a week. Blood routine check up is done in every week and iron is prescribed after 2 weeks. Result: After 4 weeks of treatment, patients were evaluated for drugs effectiveness in both groups; total effectiveness were 58.34% and 20% respectively, P >0.05; after 4 weeks of treatment, there was distinct statistical significance. Comparing with pretreatment level, Treatment group has remarkable rise in Hb after 4 weeks (81.29±9.85)对(65.75±12.37),(P<0.01, whereas control group has not distinct change in Hb level(86.95±11.61)对(84.30±16.25),(P>0.05. Conclusion: Hb is significantly increased after the use of rHuEPO and side effects were less with well tolerances.
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