经典药物及其在COVID-19治疗中的新作用

V. Wiwanitkit
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引用次数: 1

摘要

9 COVID-19是一种新出现的病毒感染,已经引起全球公共卫生问题[1-3]。已有220多个国家/地区受到攻击,全世界有1700多万患者。患者可有发热性呼吸道疾病,也有许多无症状和症状轻微的病例。这种新的病毒性呼吸道感染引起了一些医疗和非医疗问题,是一项巨大的挑战。作为一种新疾病,目前的诊断和治疗知识有限。目前,仍没有治疗COVID-19的金标准治疗方案。治疗必须依靠对症和支持性治疗。据报道,这种疾病的高死亡率导致迫切需要找到新的治疗方法来控制感染。正在进行的针对致病性病毒的新药研究和开发是疾病控制成功的希望。然而,通常需要很长时间才能找到一种新药来治疗一种新出现的疾病。此外,COVID-19是一种新的病毒性疾病,寻找有效的药物通常很困难。为进一步开发寻找一种新的替代前药需要很长时间,它可能及时应对目前的疫情危机。因此,从经典药物中寻找新药的想法是非常有趣的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Classical Drug and its New Role in COVID-19 Management
9 COVID-19 is the new emerging viral infection that already cause global public health problem [1-3]. More than 220 countries/territories are already attacked and there are more than 17 million patients around the world. This disease was firstly reported in China then in Indochina and extended worldwide. The patient can have febrile respiratory illness and there are many asymptomatic and mild symptomatic cases. The new viral respiratory infection causes several medical and non-medical problems and it is a big challenge to be managed. As a new disease, the knowledge on diagnosis and management is limited. At present, there is still no gold standard therapeutic regimen for managing COVID-19. The treatment has to depend on symptomatic and supportive treatment. The high mortality rate of this disease is reported and it leads to the urgent need to find new therapeutic method to manage the infection. The ongoing researches and developments for finding new drug against the pathogenic virus is the hope for success in disease containment [4]. Nevertheless, it usually takes a very long time to find a new drug for management of a new emerging disease. Additionally, COVID-19 is a new viral disease, finding the effective drug is usually difficult. Seeking a new alternative prodrug for further development has to take a long time and it might be in time for managing the present outbreak crisis. Therefore, the ideas for seeking new drug from classic drugs is very interesting.
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