先天性心脏病对儿童自闭症谱系障碍发展的影响

IF 0.9 Q3 EDUCATION & EDUCATIONAL RESEARCH
Dhriti P. Shah, Jothsna Kethar
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引用次数: 0

摘要

众所周知,先天性心脏病(CHD)会导致终生的健康并发症,特别是如果它在生命早期损害了其他身体功能。其中一种并发症是发展为严重的神经发育障碍的风险,即自闭症谱系障碍(AuSD)。通过一些案例研究确定了冠心病和澳元性心律失常之间的联系,已经成功地确定了被诊断患有冠心病确实会增加儿童在以后的生活中患澳元性心律失常的机会。为什么会出现这种情况,没有一个简单的答案。然而,有几个因素可以导致冠心病增加患自闭症的风险。一些可能的解释可能包括一些合成因素,如早期心脏手术导致遗传途径中血流的改变。这些解释也可能包括不可控因素,如人口统计、产妇状况和病毒感染,所有这些因素都与合成因素一样可能。本研究基于最近进行的病例研究,进一步强化了冠心病某些病变的诊断会导致发生AuSD的风险增加的结论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effects of Congenital Heart Disease on the Development of Autism Spectrum Disorder in Pediatric Patients
It is a well-known fact that congenital heart disease (CHD) can cause life-long health complications, especially if it impairs other bodily functions early in life. One of these complications is the risk of developing a serious neurodevelopmental disorder known as autism spectrum disorder (AuSD). With some case studies identifying the linkage of CHD and AuSD, it has been successfully established that being diagnosed with CHD does increase a child’s chances of developing AuSD later in life. There is not a simple answer for why this occurs. However, there are several factors that can contribute to why CHD increases the risk of developing autism. Some possible explanations may include synthetic factors such as the alteration of blood flow in genetic pathways due to early cardiac surgery. These explanations can also include uncontrollable factors such as demographics, maternal conditions, and viral infections, all of which are just as likely as synthetic factors. This research, based on case studies conducted recently, further reinforces the conclusion that the diagnosis of certain lesions of CHD results in an elevated risk of developing AuSD. 
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来源期刊
Journal of Student Affairs Research and Practice
Journal of Student Affairs Research and Practice EDUCATION & EDUCATIONAL RESEARCH-
CiteScore
2.40
自引率
9.10%
发文量
50
期刊介绍: The vision of the Journal of Student Affairs Research and Practice (JSARP) is to publish the most rigorous, relevant, and well-respected research and practice making a difference in student affairs practice. JSARP especially encourages manuscripts that are unconventional in nature and that engage in methodological and epistemological extensions that transcend the boundaries of traditional research inquiries.
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