胡芦巴籽提取物中皂苷-纳米银绿片的制备及评价

ECSOC-25 Pub Date : 2021-11-14 DOI:10.3390/ecsoc-25-11765
J. Patil, Hamid Sayyed, H. Suryawanshi, Bhavika Patil
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引用次数: 5

摘要

目前,由于几种应用,纳米粒子的需求量很大。商业上使用的金属纳米颗粒通常由合成化学物质组成。这些化学物质有毒且可燃。目前的研究目的是探索利用草药材料制备纳米颗粒的优势;因此,我们开发了葫芦巴种子水提物的银纳米颗粒,并将其配制成片剂。胡芦巴籽含有甾体皂苷元,有助于降低血液胆固醇水平,控制糖尿病,促进母乳分泌,帮助消化,并有助于减肥,因此可以在上述所有情况下推荐配制配方。对配方的预压缩参数分别为容重、攻丝密度、卡尔指数、豪斯纳比和休止角,结果分别为0.16 gm/cc、0.86 gm/cc、14.16、1.13和32◦;压缩后参数为重量变化、脆性、硬度、厚度和崩解,结果分别为0.504 gm、0.2%、3.21 gm/ cm2、2.55 mm和7 min。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Formulation and Evaluation of Verdant Tablets Containing Saponin-Coalesced Silver Nanoparticles Got from Fenugreek Seed Extract
: Presently, nanoparticles are in demand due to several applications. Commercially used metallic nanoparticles are usually comprised of synthetic chemicals. These chemicals are noxious and combustible. Current research had the objective to explore the advantages of nanoparticles using herbal material; hence, we developed silver nanoparticles of aqueous extract of Trigonellafoenum graecum (Fenugreek) seeds and formulated them into tablets. Fenugreek seeds contain steroidal sapogenins and are responsible for the reduction of blood cholesterol levels, control diabetes, enhance breast milk production, digestion aid, and helps in weight loss hence prepared formulation can be recommended in all the above cases. The pre-compression parameters evaluated for formulations are bulk density, tapped density, Carr’s index, Hausner’s ratio, and angle of repose, and the results are 0.16 gm/cc, 0.86 gm/cc, 14.16, ratio 1.13 and 32 ◦ , respectively; whereas post-compression parameters are weight variation, friability, hardness, thickness, and disintegration, and the results are 0.504 gm, 0.2%, 3.21 gm/cm 2 , 2.55 mm, and 7 min, respectively.
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