Crohn’s Disease Concurrent with Hemoglobin E (HbE) Disease Manifested as Melaena with Severe Anaemia

Hemoglobin E (HbE) disease is an inherited autosomal recessive disorder presented as mild anaemia and occasionally a slightly enlarged spleen but usually do not have disease symptoms and do not require treatment. Crohn’s disease is an uncommon inflammatory bowel disease having relapsing and remitting course usually extending over years involving any part of the gastrointestinal tract presenting as abdominal pain, diarrhea and weight loss, a rare disease in Bangladesh. Here we are presenting a case of 23-year- old female of HbE disease with melaena and severe anaemia who later diagnosed as Crohn’s disease concurrent with HbE disease.