前列腺癌患者先进放疗技术计算dvh与测量dvh的评价研究

I. Elhamamsi, K. Elshahat, A. El-Shershaby, T. Hegazy
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引用次数: 0

摘要

本研究旨在使用3DVH软件(Sun Nuclear Corporation, Melbourne, FL, USA)比较治疗计划系统(TPS)预测的剂量与ArcCHECK剂量计装置获得的测量剂量,采用两种先进的治疗技术:体积调制电弧治疗(VMAT)和强度调制放射治疗(IMRT)。本研究采用Eclipse计划系统对30例前列腺癌患者行VMAT治疗后再行IMRT。采用3DVH软件计算剂量差百分比(%DDs),规划靶体积(PTV)和危险器官(OARs)。研究了%DD与γ通过率(GPR) (3%/3mm, 2%/2mm和1%/1mm)标准之间的相关性。使用不同的PTV和OAR参数,比较3DVH计算的dvh和TPS预测的dvh。在VMAT技术中,PTV的%DD小于3%,OAR的%DD小于4%,而IMRT技术中PTV的%DD小于2%,OAR的%DD小于4%。与ArcCHECK相比,3DVH与VMAT计划验证数据更加一致,在3%/ 3mm标准下,平均伽马通过率为99.34%。基于我们的结果,VMAT对前列腺大多数癌症的治疗尤其有益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluative study between calculated and measured DVHs for advance techniques of radiotherapy for Prostate Cancer Patients
This study aims to use 3DVH software (Sun Nuclear Corporation, Melbourne, FL, USA) to compare the dose that was predicted by treatment planning system (TPS) with the measured dose obtained by ArcCHECK dosimetric device using two advance treatment techniques: Volumetric Modulated Arc Therapy (VMAT) and Intensity Modulated Radiation Therapy (IMRT). Thirty prostate cancer patients who were treated with VMAT and replanned with IMRT using Eclipse planning system were studied. The percentage dose differences (%DDs) were calculated using 3DVH software for planning target volume (PTV) and risk organ (OARs). The correlations between %DD and the gamma pass rate (GPR) (3%/3mm, 2%/2mm and 1%/1mm) criterion were examined. Both the DVHs calculated by 3DVH and the one projected by TPS were compared using the different parameters for PTV and OAR. In VMAT technique, the %DD was less than 3% for PTV and 4% for OAR while the IMRT technique recorded %DD less than 2% for PTV and 4% for OAR. 3DVH was somewhat more consistent with the planned VMAT verification data compared to ArcCHECK, with a mean gamma pass rate of 99.34% for the 3%/3 mm criterion Based on our results, VMAT is especially beneficial for prostate most cancers treatment.
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