在体外开发的模型系统中，邻苯二甲酸丁苯酯诱导修饰的证据

Analusis Pub Date : 2000-11-01 DOI:10.1051/ANALUSIS:2000153

M. Sabbieti, L. Marchetti, R. Curini, G. Menghi, A. Roda, M. V. Russo, C. Nugnes, S. Materazzi

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引用次数: 7

摘要

在体外模型系统中监测了邻苯二甲酸盐对成骨细胞的诱导修饰:通过量热法(DSC)、共聚焦激光扫描显微镜(CLSM)和耦合气相色谱-质谱法(GC-MS)独立获得的初步令人鼓舞的结果显示，将动力学数据和免疫荧光图像联系起来的可能性，这对显示邻苯二甲酸盐进入细胞和定位非常有用。量热数据是通过细胞活系统生长和与铝锅反应得到的。

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Evidence of butyl benzyl phtalate induced modifications in a model system developed in vitro

The phtalate induced modifications on osteoblastic cells have been monitored in a model system in vitro: preliminary encouraging results, independently obtained by calorimetry (DSC), confocal laser scanning microscopy (CLSM) and coupled gas chromatography-mass spectrometry (GC-MS), show the possibility to relate kinetic data and immunofluorescence images, that are very useful to show the entry and the localization of phtalate into the cells. The calorimetric data were obtained by a cellula r liv- ing system growth and reacting into the aluminium pans.

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Analusis

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