HLA-G和HLA-E:基础和病理生理方面

Immunology today Pub Date : 2000-11-01 DOI:10.1016/S0167-5699(00)01707-2

Edgardo D. Carosella , Pascale Paul , Philippe Moreau , Nathalie Rouas-Freiss

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引用次数: 110

摘要

1998年举行的第一届国际HLA-G会议使我们得出结论，HLA-G是来自主要组织相容性复合体(MHC)的耐受分子，在母胎耐受中起重要作用，可能在肿瘤和移植中也起重要作用。第二届国际HLA-G*会议的重点是HLA-G的病理生理，并扩展到HLA-E和HLA-F。

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HLA-G and HLA-E: fundamental and pathophysiological aspects

The First International Conference on HLA-G, held in 1998, led us to the conclusion that HLA-G is a tolerance molecule from the major histocompatibility complex (MHC) that plays an important role in maternal–fetal tolerance and probably in tumors and transplantation. The Second International Conference on HLA-G^* focused on the pathophysiology of HLA-G and was extended to HLA-E and HLA-F.

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Immunology today

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