E. Šovčíková, M. Ursínyová, L. Wsólová, V. Rao, M. Lustik
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引用次数: 4
摘要
对居住在斯洛伐克共和国布拉迪斯拉发的395名9-10岁儿童进行了横断临床评估,以检查低血铅水平(PbB)对神经运动和认知能力的潜在不利影响。进行了8项临床评估,包括神经运动测试(简单反应时间、维也纳、敲击测试)和认知测试(Benton、Bender、Raven和WISC1和2)。全血铅水平作为铅身体负荷水平的替代指标。研究人群的平均PbB为36.5 ug/L (SD-16.2)。在研究人群中,PbB与整体智力(Raven, p <.001)、视觉短期记忆(Benton, p <.05)以及教师和家长的活动评价(p <.05)之间存在统计学上显著的负相关。在多变量分析中纳入了8个协变量,以检验社会经济因素对pbb测试绩效关系的混淆效应。观察到一个非常显著的负相关…
EFFECTS ON THE MENTAL AND MOTOR ABILITIES OF CHILDREN EXPOSED TO LOW LEVELS OF LEAD IN BRATISLAVA
A cross-sectional clinical evaluation was performed on 395 children aged 9-10 yr residing in Bratislava, Republic of Slovakia, to examine the potential adverse effects of low lead levels in blood (PbB) on neuromotor and cognitive performance. Eight clinical evaluations comprised of neuromotor (simple reaction time, Vienna, tapping test) and cognitive tests (Benton, Bender, Raven, and WISC1 and 2) were conducted. Whole blood lead levels served as the surrogate for lead body-burden levels. The mean PbB of the study population was 36.5 ug/L (SD-16.2). A statistically significant negative association between PbB and global intelligence (Raven, p <.001) visual short-term memory (Benton, p <.05), and activity evaluations by teachers and parents ( p <.05) was observed in the study population. Eight covariates were included in a multivariate analysis to examine the confounding effects of socioeconomic factors on the PbB-test performance relationship. A highly significant negative association was observed...