Vinod Kumar, A. Choudhary, Prashanth Kumar, Saurabh Sharma
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Nanotechnology: Nanomedicine, Nanotoxicity and Future Challenges
This review gives an overview of interesting properties of nanoparticles
finding potential applications in nanomedicines and their considerations that need to be made such
as toxicity while developing a nanomedicine by providing an understanding of a relationship between
nanocarrier, targeting moieties and drugs with optical and magnetic properties. Here, we correlate
the interesting properties of nanomaterials to their applications in living cells/body simultaneously
promises, prospects and toxicity challenges of nanomedicines have also been discussed in
detail. Exemplifying the usage of gold nanoparticles and its derivatives such as hetero and homo
hybrid nanostructures that allow their use as contrast agents, therapeutic entities and supports to attach
functional molecules and targeting ligand along with molecular framework structures. Here,
we present the future prospects for potential applications in nanomedicines. These nanomaterials
have been used for varieties of biomedical applications such as targeted drug delivery, photothermal
cancer therapies, MRI, optical imaging, etc. in vitro and in vivo.
In summary, this review provides innumerable aspects in the emerging field of
nanomedicine and possible nanotoxicity.