Frederick Sarfo-Antwi, Christopher Larbie, B. Emikpe, R. Appiah-Opong
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引用次数: 0
摘要
豆科周参(Pericopsis laxiflora)是一种普遍存在于热带和大草原地区的药用植物。有许多关于民间和传统医学用途的报告,包括痔疮、风湿病、腹痛、腹泻和痢疾、发烧、皮肤病和黄疸的治疗。通过查阅Scopus、Medline、Web of Science、PubMed、Science Direct和Google Scholar等数据库收集同行评议文章。植物化学研究发现了许多具有生物活性的化合物,如β-碳碱衍生物和色胺衍生物。该植物已在体外、体内或临床评价的基础上进行了检验,并显示出主要的药理活性。这些包括抗锥虫、抗微生物、抗菌、抗氧化和抗疟疾活性。在本综述文章Sarfo-Antwi等;生物工程学报,30(2):1-7,2021;文章no.IJBCRR。摘要本文综述了近年来国内外对其植物化学和药理方面的研究进展。必须对该植物进行全面的安全性和有效性研究。一般来说,存在必须填补的知识空白。因此,本文旨在为民族药理学、天然产物化学和药物发现相关研究领域的从业者和研究人员提供参考。
Ethnobotany, Phytochemistry and Pharmacology of Pericopsis laxiflora (Baker) Meeuwen (Leguminosae) – A Review
Pericopsis laxiflora (Family Leguminosae) is a medicinal plant that is ubiquitous especially in the tropical and savannah regions. There are many reports on folkloric and traditional medicinal uses that include haemorrhoids, rheumatism, abdominal pain treatment, diarrhoea, and dysentery, fever, skin diseases and jaundice. Peer-reviewed articles were gathered by consulting the databases of Scopus, Medline, Web of Science, PubMed, Science Direct and Google Scholar. Phytochemical investigations have revealed many bioactive compounds such as β-carboline derivative and tryptamine derivative. The plant has been examined on the basis of the in vitro, in vivo or clinical evaluations and shown to possess major pharmacological activities. These include antitrypanosomal, antimicrobial, antibacterial, antioxidant and anti-malarial activities. In the present Mini-review Article Sarfo-Antwi et al.; IJBCRR, 30(2): 1-7, 2021; Article no.IJBCRR.64206 2 review, an attempt has been made to congregate the traditional, phytochemical and pharmacological studies performed on Pericopsis laxiflora. Comprehensive safety and efficacy studies must be conducted on the plant. Generally, there are knowledge gaps that must be filled. Thus this review is intended for practitioners and researchers in the fields of ethnopharmacology, natural product chemistry and drug discovery related research.