A. Debache, Louisa Chouguiat, R. Boulcina, B. Carboni
{"title":"无溶剂条件下，t-BuOK催化Biginelli缩合和Hantzsch缩合一锅多组分合成二氢嘧啶/硫酮和二氢吡啶衍生物","authors":"A. Debache, Louisa Chouguiat, R. Boulcina, B. Carboni","doi":"10.2174/1874095201206010012","DOIUrl":null,"url":null,"abstract":"The synthesis of various substituted Biginelli 3,4-dihydropyrimidinone/thione and Hantzsch 1,4- dihydropyridine derivatives has been achieved using a modified procedure in the presence of potassium ter-butoxide (t- BuOK) as a catalyst under solvent-free conditions, in good to excellent yields.","PeriodicalId":23020,"journal":{"name":"The Open Organic Chemistry Journal","volume":"89 1","pages":"12-20"},"PeriodicalIF":0.0000,"publicationDate":"2012-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"29","resultStr":"{\"title\":\"A One-pot Multi-component Synthesis of Dihydropyrimidinone/Thione and Dihydropyridine Derivatives via Biginelli and Hantzsch Condensations using t-BuOK as a Catalyst Under Solvent-free Conditions\",\"authors\":\"A. Debache, Louisa Chouguiat, R. Boulcina, B. Carboni\",\"doi\":\"10.2174/1874095201206010012\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The synthesis of various substituted Biginelli 3,4-dihydropyrimidinone/thione and Hantzsch 1,4- dihydropyridine derivatives has been achieved using a modified procedure in the presence of potassium ter-butoxide (t- BuOK) as a catalyst under solvent-free conditions, in good to excellent yields.\",\"PeriodicalId\":23020,\"journal\":{\"name\":\"The Open Organic Chemistry Journal\",\"volume\":\"89 1\",\"pages\":\"12-20\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"29\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Open Organic Chemistry Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874095201206010012\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Open Organic Chemistry Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874095201206010012","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A One-pot Multi-component Synthesis of Dihydropyrimidinone/Thione and Dihydropyridine Derivatives via Biginelli and Hantzsch Condensations using t-BuOK as a Catalyst Under Solvent-free Conditions
The synthesis of various substituted Biginelli 3,4-dihydropyrimidinone/thione and Hantzsch 1,4- dihydropyridine derivatives has been achieved using a modified procedure in the presence of potassium ter-butoxide (t- BuOK) as a catalyst under solvent-free conditions, in good to excellent yields.
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