高阶种子模式的运行概率及其在寻找好的过渡种子中的应用

Jialiang Yang, Louxin Zhang
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引用次数: 1

摘要

过渡种子在编码区和非编码区同源性搜索中表现出良好的敏感性和特异性之间的平衡。但是,确定好的过渡种子是非常困难的。我们研究了高阶种子模式的命中概率。基于我们的理论结果,我们提出了一种用于种子设计的过渡种子排序的高效方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Run Probability of High-Order Seed Patterns and its Applications to Finding Good Transition Seeds
Transition seeds exhibit a good tradeofi between sensitivity and speciflcity for homology search in both coding and non-coding regions. But, identifying good transition seeds is extremely hard. We study the hit probability of high-order seed patterns. Based on our theoretical results, we propose an e‐cient method for ranking transition seeds for seed design.
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