METHODOLOGY FOR THE APPLICATION OF THE SUPRAMOLECULAR COMPLEX OF IVERMECTIN "ANIVERM-2.0%" AGAINST PARASITOSIS OF HERD HORSES

Deworming untamed herd horses is a difficult task. It is more convenient to use drugs by free feeding, individually or in groups in a mixture with concentrated feed. In this regard, we have developed a new dosage form for the treatment and prevention of parasitosis in herd horses by free feeding in a mixture with concentrated feed based on the substance ivermectin, which has a high antiparasitic activity and a wide spectrum of action. To obtain an antiparasitic supramolecular complex based on the substance ivermectin, an innovative mechanochemical technology was used using two water-soluble polymers of low molecular weight polyvinylpyrrollydon-17 and natural arabinogalactan. The aim of the work is to develop a methodology for the use of the supramolecular complex ivermectin "Aniverm-2.0%" against parasitosis of herd horses. The drug "Aniverm-2.0%" is a supramolecular complex of ivermectin, a water-soluble solid powder of a light beige color, tasteless, with an easily perceptible coniferous odor. The methodology provides a brief description of the drug, its mechanism of action, pharmaco-toxicological properties, the procedure for use, the timing of slaughtering animals and personal safety measures. According to the degree of impact on the body of warm-blooded animals, the drug "Aniverm-2.0%" belongs to low-toxic substances.