糖尿病患者体内宏观、微观和超微观转化的机制

I. Savka, M.N. Tsytovskyi, G. Dmytriv
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引用次数: 0

摘要

研究糖尿病患者的器官和组织结构变化是现代医学亟待解决的问题之一。据世卫组织称,在世界所有国家,糖尿病患者人数超过1.75亿。据专家估计,到2025年这种疾病的传播将使3亿人左右。乌克兰官方登记的糖尿病患者已超过100万。世卫组织已确认该病为非传染性流行病。糖尿病发病率的急剧上升要求对这个问题进行详细的研究。根据地区、国家经济发展水平、性别和年龄的不同,世界各国人口中糖尿病的患病率呈上升趋势。因此,根据国际糖尿病论坛的调查结果,发展中国家40至59岁的城市(城市)健全人口中糖尿病患病率最高的趋势是男性和女性大致相等。患者数量正在增加,主要是由于2型糖尿病患者。2型糖尿病(2型糖尿病)是一种严重的进行性慢性疾病,是心力衰竭(CH)和心血管并发症的独立危险因素。在21世纪。2型糖尿病的稳步增长及其严重后果的频繁发生引起了世界医学界的极大关注。重要的是,在诊断2型糖尿病时,导致生活质量下降、早期残疾和过早死亡的并发症的发生率已经足够高。尽管在与这一疾病的斗争中存在有效的药物、现代技术、新的教育和预防技术,但人类在与糖尿病的斗争中年复一年地失败,糖尿病因其并发症而导致残疾,降低了患者的预期寿命和生活质量,丧失了工作能力和过早死亡。因此,目前糖尿病和危及生命的并发症的流行和发病率表明,在世界上,特别是在乌克兰,存在一种非传染性糖尿病流行病。这篇文章代表了许多研究人员的工作分析,他们研究了糖尿病对心血管系统影响的统计、临床和形态学方面。对糖尿病并发症的主要形态发生、形态学和临床方面、糖尿病患者微循环病理进行了探讨,为糖尿病血管并发症的早期预测和发现提供了可能,并进行有效的预防和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mechanisms of macro-, micro- and ultramicroscopic transformation of bodies in diabetes
The study of structural changes of organs and tissues in the context of diabetes is one of the urgent problems of modern medicine. According to WHO, in all countries of the world the number of patients with diabetes exceeds 175 million. According to an expert estimate of the spread of this disease by 2025 will make about 300 million people. More than 1 million people with diabetes have been officially registered in Ukraine. WHO has recognized the disease as a non-communicable epidemic. The dramatic increase in the prevalence of diabetes requires a detailed study of this problem. It is established that the prevalence of diabetes increases among the population of the countries of the world depending on the region, the level of economic development of the country, gender and age. Thus, according to IDF findings, there is a tendency for the highest prevalence of diabetes among the urban (urban) able-bodied population of developing countries in persons between 40 and 59 years of age, approximately equal in both male and female. The number of patients is increasing, mainly due to patients with type 2 diabetes. Type 2 diabetes (type 2 diabetes mellitus) is a severe progressive chronic disease that is an independent risk factor for heart failure (CH) and cardiovascular complications. In the XXI century. the steady growth of type 2 diabetes and the frequency of its serious consequences is of great concern to the world medical community. It is important that at the time of diagnosis of type 2 diabetes, the prevalence of complications leading to a decline in quality of life, early disability and premature death is already high enough. Despite the presence in the fight against this disease effective drugs, modern technologies, new educational and preventive techniques, mankind loses the fight against diabetes year after year, which leads to disability due to its complications, reducing the life expectancy and quality of life of patients, loss working capacity and premature mortality. Thus, the current prevalence and incidence of diabetes and life-threatening complications suggest that there is a non-communicable diabetes epidemic in the world and in Ukraine in particular. The article represents analysis of work of numerous researchers who studied statistіcal, clinical and morphological aspects of the impact of diabetes on cardiovascular system. Main morphogenetic, morphological and clinical aspects of complications of diabetes, pathologies of microcirculation of patients with diabetes were dedicated, what makes possible to predict and detect on the early stages vascular complications in diabetes and to perform effective prevention and treatment.
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