Direct and combined effects of ozone on biofilm Pseudomonas aeruginosa

In modern medicine, the issue of combating biofilms, including various surfaces in medical facilities, is acute. Ozonation is an environmentally friendly and effective technology in the fight against microbial pollution, including biofilms. The article presents studies of the disinfecting properties of ozone and its combination with various disinfectants on planktonic and adhered (in the biofilm form) Pseudomonas aeruginosa cells. As a result, it was found that ozone is highly effective against various forms of bacterial life, and also requires longer exposure in the presence of organic pollution. When combined with hydrogen peroxide, it shows the greatest bactericidal effect not only on the destruction of the biofilm, but also on the viability of the cells themselves. Keywords: biofilm, ozone disinfection, destruction of biofilm.