{"title":"将抗生素Ceftriaxone和Ciprofloxacine对膀胱感染病例进行比较","authors":"Sasangka H. Wardhana, A. Monoarfa, R. Monoarfa","doi":"10.35790/JBM.10.3.2018.21984","DOIUrl":null,"url":null,"abstract":"Abstract: Urinary tract infection (UTI) is the most common infection affecting about 40% of women in their lives. Most infections are mild, albeit, they might cause sepsis. This study was aimed to compare the effectiveness of ceftriaxone to ciprofloxacin in patients with UTIs at Prof. Dr. R. D. Kandou Hospital Manado. This was an observational study with a cross sectional design implemented from September 2017 until January 2018. Subjects were divided into two groups, Gram positive and Gram negative bacterial infections. Data were analyzed by using the chi-Square test. The results showed that in the Gram negative group, the significance value did not support the difference between efficacy of ciprofloxacin and of ceftriaxone (r = 0.366; P >0.05). However, in the Gram positive group, there was a significant difference (r = 0.003; P <0.05) between the efficacy of the two kinds of antibiotics. Conclusion: Ciprofloxacin was more effective compared to ceftriaxone for the treatment of Gram positive urinary tract infectionKeywords: urinary tract infection (UTI), ceftriaxone, ciprofloxacineAbstrak: Infeksi saluran kencing (ISK) merupakan infeksi tersering yang mengenai sekitar 40% dari populasi perempuan dalam hidupnya. Walaupun umumnya infeksi berlangsung ringan, ISK dapat juga menyebabkan sepsis. Penelitian ini bertujuan untuk membandingkan efektivitas ceftriaxone dan ciprofloxacin pada pasien dengan ISK di RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ialah observasional dengan desain potong lintang. Penelitian ini dilaksanakan sejak September 2017 sampai Januari 2018. Subyek penelitian dibagi dalam dua kelompok, ISK oleh bakteri Gram positif dan oleh Gram negatif. Data dianalisis menggunakan chi-square test. Hasil penelitian memperlihatkan bahwa pada kelompok Gram negatif, tidak terdapat perbedaan bermakna antara efektivitas ciprofloxacin dan ceftriaxone (r=0,366; P>0,05) namun pada kelompok Gram positif, terdapat perbedaan bermakna antara efektivitas kedua jenis antibiotik (r=0,003; P<0,05). Simpulan: Ciprofloxacin lebih efektif dibandingkan ceftriaxone pada pengobatan ISK yang disebabkan oleh bakteri Gram positif.Kata kunci: infeksi saluran kencing (ISK), ceftriaxone, ciprofloxacine","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"53 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Perbandingan Efektifitas Antibiotik Ceftriaxone dan Ciprofloxacine pada Penderita Infeksi Saluran Kemih di RSUP Prof. Dr. R. D. Kandou Manado\",\"authors\":\"Sasangka H. Wardhana, A. Monoarfa, R. Monoarfa\",\"doi\":\"10.35790/JBM.10.3.2018.21984\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract: Urinary tract infection (UTI) is the most common infection affecting about 40% of women in their lives. Most infections are mild, albeit, they might cause sepsis. This study was aimed to compare the effectiveness of ceftriaxone to ciprofloxacin in patients with UTIs at Prof. Dr. R. D. Kandou Hospital Manado. This was an observational study with a cross sectional design implemented from September 2017 until January 2018. Subjects were divided into two groups, Gram positive and Gram negative bacterial infections. Data were analyzed by using the chi-Square test. The results showed that in the Gram negative group, the significance value did not support the difference between efficacy of ciprofloxacin and of ceftriaxone (r = 0.366; P >0.05). However, in the Gram positive group, there was a significant difference (r = 0.003; P <0.05) between the efficacy of the two kinds of antibiotics. Conclusion: Ciprofloxacin was more effective compared to ceftriaxone for the treatment of Gram positive urinary tract infectionKeywords: urinary tract infection (UTI), ceftriaxone, ciprofloxacineAbstrak: Infeksi saluran kencing (ISK) merupakan infeksi tersering yang mengenai sekitar 40% dari populasi perempuan dalam hidupnya. Walaupun umumnya infeksi berlangsung ringan, ISK dapat juga menyebabkan sepsis. Penelitian ini bertujuan untuk membandingkan efektivitas ceftriaxone dan ciprofloxacin pada pasien dengan ISK di RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ialah observasional dengan desain potong lintang. Penelitian ini dilaksanakan sejak September 2017 sampai Januari 2018. Subyek penelitian dibagi dalam dua kelompok, ISK oleh bakteri Gram positif dan oleh Gram negatif. Data dianalisis menggunakan chi-square test. Hasil penelitian memperlihatkan bahwa pada kelompok Gram negatif, tidak terdapat perbedaan bermakna antara efektivitas ciprofloxacin dan ceftriaxone (r=0,366; P>0,05) namun pada kelompok Gram positif, terdapat perbedaan bermakna antara efektivitas kedua jenis antibiotik (r=0,003; P<0,05). Simpulan: Ciprofloxacin lebih efektif dibandingkan ceftriaxone pada pengobatan ISK yang disebabkan oleh bakteri Gram positif.Kata kunci: infeksi saluran kencing (ISK), ceftriaxone, ciprofloxacine\",\"PeriodicalId\":17726,\"journal\":{\"name\":\"JURNAL BIOMEDIK (JBM)\",\"volume\":\"53 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JURNAL BIOMEDIK (JBM)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.35790/JBM.10.3.2018.21984\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JURNAL BIOMEDIK (JBM)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35790/JBM.10.3.2018.21984","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
摘要:尿路感染(UTI)是最常见的感染,约有40%的女性在其生活中受到影响。大多数感染是轻微的,尽管它们可能导致败血症。这项研究的目的是比较头孢曲松和环丙沙星在万那多市坎杜医院的尿路感染患者中的疗效。这是一项观察性研究,采用横断面设计,于2017年9月至2018年1月实施。受试者分为革兰氏阳性和革兰氏阴性细菌感染两组。数据分析采用卡方检验。结果显示,在革兰氏阴性组,显著性值不支持环丙沙星与头孢曲松的疗效差异(r = 0.366;P > 0.05)。而革兰氏阳性组差异有统计学意义(r = 0.003;(P < 0.05) namun pada kelpok Gram阳性,terdapat perbeda和bermakna antara ektivitas keduis抗生素(r=0,003;P < 0 05)。实验结果表明:环丙沙星、头孢曲松、苯丙沙星、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪、黄芪。Kata kunci:消炎治疗(ISK),头孢曲松,环丙沙星
Perbandingan Efektifitas Antibiotik Ceftriaxone dan Ciprofloxacine pada Penderita Infeksi Saluran Kemih di RSUP Prof. Dr. R. D. Kandou Manado
Abstract: Urinary tract infection (UTI) is the most common infection affecting about 40% of women in their lives. Most infections are mild, albeit, they might cause sepsis. This study was aimed to compare the effectiveness of ceftriaxone to ciprofloxacin in patients with UTIs at Prof. Dr. R. D. Kandou Hospital Manado. This was an observational study with a cross sectional design implemented from September 2017 until January 2018. Subjects were divided into two groups, Gram positive and Gram negative bacterial infections. Data were analyzed by using the chi-Square test. The results showed that in the Gram negative group, the significance value did not support the difference between efficacy of ciprofloxacin and of ceftriaxone (r = 0.366; P >0.05). However, in the Gram positive group, there was a significant difference (r = 0.003; P <0.05) between the efficacy of the two kinds of antibiotics. Conclusion: Ciprofloxacin was more effective compared to ceftriaxone for the treatment of Gram positive urinary tract infectionKeywords: urinary tract infection (UTI), ceftriaxone, ciprofloxacineAbstrak: Infeksi saluran kencing (ISK) merupakan infeksi tersering yang mengenai sekitar 40% dari populasi perempuan dalam hidupnya. Walaupun umumnya infeksi berlangsung ringan, ISK dapat juga menyebabkan sepsis. Penelitian ini bertujuan untuk membandingkan efektivitas ceftriaxone dan ciprofloxacin pada pasien dengan ISK di RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ialah observasional dengan desain potong lintang. Penelitian ini dilaksanakan sejak September 2017 sampai Januari 2018. Subyek penelitian dibagi dalam dua kelompok, ISK oleh bakteri Gram positif dan oleh Gram negatif. Data dianalisis menggunakan chi-square test. Hasil penelitian memperlihatkan bahwa pada kelompok Gram negatif, tidak terdapat perbedaan bermakna antara efektivitas ciprofloxacin dan ceftriaxone (r=0,366; P>0,05) namun pada kelompok Gram positif, terdapat perbedaan bermakna antara efektivitas kedua jenis antibiotik (r=0,003; P<0,05). Simpulan: Ciprofloxacin lebih efektif dibandingkan ceftriaxone pada pengobatan ISK yang disebabkan oleh bakteri Gram positif.Kata kunci: infeksi saluran kencing (ISK), ceftriaxone, ciprofloxacine