药物Favipiravir在Covid-19患者刺突蛋白破坏中的作用

A. Atiyah, Faesal Hassen
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引用次数: 0

摘要

刺突蛋白是病毒的毒力因子之一,它负责病毒附着在宿主细胞上。本研究包括研究Favipiravir对S蛋白在不同浓度的影响,因为它显示效果的浓度最高的0.5和9.66的±浓度。.025 7.06±逐渐影响的(5.23±3.63±2.53±1.60±0.06±0.00)的浓度(0.015,0.03,0.06,0.125,0.07,0.02),分别作为一旦病毒与细胞宿主引起S蛋白的结构重排,这使得病毒可以与宿主细胞膜融合。由于Covid-19病毒及其成分的严重性,有必要找到一种控制大流行传播的药物。《生理与分子生物学》是埃及生物科学学术期刊的财产,未经版权所有者的明确书面许可,其内容不得复制或通过电子邮件发送到多个网站或发布到listserv。但是,用户可以打印、下载或通过电子邮件发送文章供个人使用。这可以删节。对副本的准确性不作任何保证。用户应参阅原始出版版本的材料的完整。(版权适用于所有人。)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of the Drug Favipiravir in the Destruction of Spike Protein in Patients with Covid-19
The Spike protein is one of the virulence factors of viruses, which is responsible for the attachment of the virus to the host cell. This study included the study of the effect of Favipiravir on S protein at different concentrations, as it showed the highest effect at a concentration of 0.5 and an amount of 9.66 ± followed by the concentration. .025 by 7.06 ± to have a gradual effect of (5.23 ±, 3.63 ± 2.53 ±, 1.60 ±, 0.06 ±, 0.00) at a concentration of (0.015, 0.03, 0.06, 0.125, 0.07, 0.02), respectively, as once the virus interacts with the cell The host causes a structural rearrangement of the S protein, which allows the virus to fuse with the host cell membrane. Because of the seriousness of the Covid-19 virus and its components, it has become necessary to find a drug that controls the spread of the pandemic. [ FROM AUTHOR] Copyright of Egyptian Academic Journal of Biological Sciences, C Physiology & Molecular Biology is the property of Egyptian Academic Journal of Biological Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
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