{"title":"Pictet-Spengler缩合法合成n -取代四氢异喹啉衍生物及表征","authors":"Heta A. Patel, Arun L. Patel","doi":"10.6000/1929-5030.2014.03.03.5","DOIUrl":null,"url":null,"abstract":"Synthesis of N-substituted 1,2,3,4 –tetrahydroisoquinoline derivatives and bis-isoquinoline has been carried out via a Pictet-Spengler condensation. Tetrahydroisoquinolines were obtained from 2-(3’,4’-dimethoxyphenyl) ethylamine in four steps. The entire synthesized compounds were characterized by IR, 1 H NMR and mass spectral data.","PeriodicalId":15165,"journal":{"name":"Journal of Applied Solution Chemistry and Modeling","volume":"51 1","pages":"169-174"},"PeriodicalIF":0.0000,"publicationDate":"2014-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis and Characterization of N-Substituted Tetrahydroiso-quinoline Derivatives via a Pictet-Spengler Condensation\",\"authors\":\"Heta A. Patel, Arun L. Patel\",\"doi\":\"10.6000/1929-5030.2014.03.03.5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Synthesis of N-substituted 1,2,3,4 –tetrahydroisoquinoline derivatives and bis-isoquinoline has been carried out via a Pictet-Spengler condensation. Tetrahydroisoquinolines were obtained from 2-(3’,4’-dimethoxyphenyl) ethylamine in four steps. The entire synthesized compounds were characterized by IR, 1 H NMR and mass spectral data.\",\"PeriodicalId\":15165,\"journal\":{\"name\":\"Journal of Applied Solution Chemistry and Modeling\",\"volume\":\"51 1\",\"pages\":\"169-174\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Applied Solution Chemistry and Modeling\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6000/1929-5030.2014.03.03.5\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Solution Chemistry and Modeling","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6000/1929-5030.2014.03.03.5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Synthesis and Characterization of N-Substituted Tetrahydroiso-quinoline Derivatives via a Pictet-Spengler Condensation
Synthesis of N-substituted 1,2,3,4 –tetrahydroisoquinoline derivatives and bis-isoquinoline has been carried out via a Pictet-Spengler condensation. Tetrahydroisoquinolines were obtained from 2-(3’,4’-dimethoxyphenyl) ethylamine in four steps. The entire synthesized compounds were characterized by IR, 1 H NMR and mass spectral data.
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