{"title":"含利巴米胺海藻酸钠薄膜的崩解特性及释药特性","authors":"Y. Murata, C. Maida, K. Kofuji","doi":"10.31031/RDMS.2021.15.000853","DOIUrl":null,"url":null,"abstract":"Sodium alginate [Alg-Na], an algal polysaccharide consisting of α-L-guluronate and β-Dmannuronate, is used as a food ingredient [1]. Some species of Alg-Na have been widely utilized as excipients in drug products and/or as impression materials in dentistry due to their polymeric properties and safe oral intake [2-4]. Alg-Na itself enacts a protective effect on the gastric mucosa; thus, it has been used as a medicine for the treatment of gastroesophageal reflux disease [5,6].","PeriodicalId":20943,"journal":{"name":"Research & Development in Material Science","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Disintegration Properties and Drug Release Profiles of Sodium Alginate Films Containing Rebamipide\",\"authors\":\"Y. Murata, C. Maida, K. Kofuji\",\"doi\":\"10.31031/RDMS.2021.15.000853\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Sodium alginate [Alg-Na], an algal polysaccharide consisting of α-L-guluronate and β-Dmannuronate, is used as a food ingredient [1]. Some species of Alg-Na have been widely utilized as excipients in drug products and/or as impression materials in dentistry due to their polymeric properties and safe oral intake [2-4]. Alg-Na itself enacts a protective effect on the gastric mucosa; thus, it has been used as a medicine for the treatment of gastroesophageal reflux disease [5,6].\",\"PeriodicalId\":20943,\"journal\":{\"name\":\"Research & Development in Material Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-03-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research & Development in Material Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31031/RDMS.2021.15.000853\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research & Development in Material Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31031/RDMS.2021.15.000853","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
海藻酸钠[algal - na]是一种由α- l - gulurate和β- dmannurate组成的海藻多糖，被用作食品配料[1]。一些种类的Alg-Na由于其聚合特性和安全的口服摄入而被广泛用作药物制品的赋形剂和/或牙科的印模材料[2-4]。海藻酸钠本身对胃粘膜有保护作用;因此，它已被用作治疗胃食管反流病的药物[5,6]。
Disintegration Properties and Drug Release Profiles of Sodium Alginate Films Containing Rebamipide
Sodium alginate [Alg-Na], an algal polysaccharide consisting of α-L-guluronate and β-Dmannuronate, is used as a food ingredient [1]. Some species of Alg-Na have been widely utilized as excipients in drug products and/or as impression materials in dentistry due to their polymeric properties and safe oral intake [2-4]. Alg-Na itself enacts a protective effect on the gastric mucosa; thus, it has been used as a medicine for the treatment of gastroesophageal reflux disease [5,6].
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