不可逆失血性休克的细菌研究。

W. Culbertson, W. Elstun, W. Cole, W. Altemeier
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引用次数: 7

摘要

Fine和他的同事的研究表明,细菌因素是实验动物长期失血性休克的不可逆性的原因,对这种因素的防御机制可以通过某些抗生素(主要是金霉素)的初步施用而增强。Fine et al. 1报道了一些引人注目且有趣的数据,他们将这些数据解释为细菌因素在狗的“不可逆”失血性休克的产生中起着重要作用。他们的结论部分是基于这样的发现:在他们的实验中,在失血性休克的标准化挑战中,通过初步使用某些抗生素药物,存活率显著提高。其他工人,特别是DeBakey 2,无法证明这种保护作用,也无法证明对照组和接受抗生素治疗组在死亡率上有任何显著差异。细菌因子的性质及作用方法的检测
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bacterial studies in irreversible hemorrhagic shock.
The studies of Fine and his co-workers suggested that a bacterial factor was a cause of irreversibility of prolonged hemorrhagic shock in experimental animals and that the defense mechanism against this factor could be enhanced by the preliminary administration of certain antibiotics, principally chlortetracycline (Aureomycin). Fine et al. 1 had reported dramatic and interesting data which they interpreted as indicative of a bacterial factor being important in the production of "irreversible" hemorrhagic shock in dogs. Their conclusion was based in part upon the finding that the survival rate in their experiments with a standardized challenge by hemorrhagic shock was significantly increased by the preliminary administration of certain antibiotic agents. Other workers, notably DeBakey, 2 were unable to demonstrate this protection or to demonstrate any significant difference in mortality between the control group and the group treated with antibiotics. The detection of the nature and method of action of bacterial factors
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