在与2019年新型冠状病毒相关的细胞因子风暴中使用脉冲剂量甲基强的松龙后呼吸衰竭的解决

Hamid Khederlou, A. Rostamian, Elham Nezhadseifi, Hourvash Ebrahimi-louyeh
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引用次数: 0

摘要

2019年12月中旬以来,中国湖北省武汉市爆发了一场病毒性肺炎疫情。经过病毒鉴定和分离,这种肺炎的病原体最初被称为2019新型冠状病毒(2019- ncov)。2019-nCoV与进行性细胞因子风暴有关,导致高度炎症状态,这种状态与呼吸衰竭有关。我们在此报告一例已知的类风湿性关节炎、高血压和冠状动脉搭桥手术病例,确诊为2019-nCoV,并与进行性细胞因子风暴导致呼吸衰竭有关。在皮质类固醇治疗后,呼吸衰竭和极高水平的il - 6对脉冲剂量的甲基强的松龙反应显著。我们的结论是,脉冲剂量的皮质类固醇可以有效地控制和缓解细胞因子风暴和相关的呼吸衰竭。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Resolved of Respiratory Failure Following the Use Pulse-Doses of Methylprednisolone in a Cytokine Storm Related to 2019 novel coronavirus
Since mid-December of 2019, an outbreak of pneumonia has been spread from Wuhan City, Hubei province, China, as a viralpneumonia. After virus identification and isolation, the pathogen for this pneumonia was originally called 2019 novelcoronavirus (2019-nCoV). 2019-nCoV has been associated with progressive cytokine storm leading to a hyper-inflammatorystate that this state associated with respiratory failure. We hereby reported a known case of Rheumatoid arthritis, Hypertensionand Coronary artery bypass graft that confirmed 2019-nCoV and he was associated with progressive cytokine storm leading torespiratory failure. After corticosteroid administration, respiratory failure and extremely high levels of IL6 respondeddramatically to pulse-doses of Methylprednisolone. We concluded that pulse-doses of Corticosteroids can be effective incontrolling and relieving cytokine storms and related respiratory failure.
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