Hamid Khederlou, A. Rostamian, Elham Nezhadseifi, Hourvash Ebrahimi-louyeh
{"title":"在与2019年新型冠状病毒相关的细胞因子风暴中使用脉冲剂量甲基强的松龙后呼吸衰竭的解决","authors":"Hamid Khederlou, A. Rostamian, Elham Nezhadseifi, Hourvash Ebrahimi-louyeh","doi":"10.22631/RR.2020.69997.1102","DOIUrl":null,"url":null,"abstract":"Since mid-December of 2019, an outbreak of pneumonia has been spread from Wuhan City, Hubei province, China, as a viralpneumonia. After virus identification and isolation, the pathogen for this pneumonia was originally called 2019 novelcoronavirus (2019-nCoV). 2019-nCoV has been associated with progressive cytokine storm leading to a hyper-inflammatorystate that this state associated with respiratory failure. We hereby reported a known case of Rheumatoid arthritis, Hypertensionand Coronary artery bypass graft that confirmed 2019-nCoV and he was associated with progressive cytokine storm leading torespiratory failure. After corticosteroid administration, respiratory failure and extremely high levels of IL6 respondeddramatically to pulse-doses of Methylprednisolone. We concluded that pulse-doses of Corticosteroids can be effective incontrolling and relieving cytokine storms and related respiratory failure.","PeriodicalId":87314,"journal":{"name":"Journal of rheumatology research","volume":"53 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Resolved of Respiratory Failure Following the Use Pulse-Doses of Methylprednisolone in a Cytokine Storm Related to 2019 novel coronavirus\",\"authors\":\"Hamid Khederlou, A. Rostamian, Elham Nezhadseifi, Hourvash Ebrahimi-louyeh\",\"doi\":\"10.22631/RR.2020.69997.1102\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Since mid-December of 2019, an outbreak of pneumonia has been spread from Wuhan City, Hubei province, China, as a viralpneumonia. After virus identification and isolation, the pathogen for this pneumonia was originally called 2019 novelcoronavirus (2019-nCoV). 2019-nCoV has been associated with progressive cytokine storm leading to a hyper-inflammatorystate that this state associated with respiratory failure. We hereby reported a known case of Rheumatoid arthritis, Hypertensionand Coronary artery bypass graft that confirmed 2019-nCoV and he was associated with progressive cytokine storm leading torespiratory failure. After corticosteroid administration, respiratory failure and extremely high levels of IL6 respondeddramatically to pulse-doses of Methylprednisolone. We concluded that pulse-doses of Corticosteroids can be effective incontrolling and relieving cytokine storms and related respiratory failure.\",\"PeriodicalId\":87314,\"journal\":{\"name\":\"Journal of rheumatology research\",\"volume\":\"53 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of rheumatology research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22631/RR.2020.69997.1102\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of rheumatology research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22631/RR.2020.69997.1102","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Resolved of Respiratory Failure Following the Use Pulse-Doses of Methylprednisolone in a Cytokine Storm Related to 2019 novel coronavirus
Since mid-December of 2019, an outbreak of pneumonia has been spread from Wuhan City, Hubei province, China, as a viralpneumonia. After virus identification and isolation, the pathogen for this pneumonia was originally called 2019 novelcoronavirus (2019-nCoV). 2019-nCoV has been associated with progressive cytokine storm leading to a hyper-inflammatorystate that this state associated with respiratory failure. We hereby reported a known case of Rheumatoid arthritis, Hypertensionand Coronary artery bypass graft that confirmed 2019-nCoV and he was associated with progressive cytokine storm leading torespiratory failure. After corticosteroid administration, respiratory failure and extremely high levels of IL6 respondeddramatically to pulse-doses of Methylprednisolone. We concluded that pulse-doses of Corticosteroids can be effective incontrolling and relieving cytokine storms and related respiratory failure.