用Ames试验评价番茄红素的致突变性。

K. Aizawa, T. Inakuma, S. Oshima
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引用次数: 5

摘要

番茄红素是番茄制品中的一种碳氢类胡萝卜素。采用Ames试验对番茄红素进行诱变性检测,以评价番茄红素的安全性。将从番茄酱中提取的番茄红素作为溶液或悬浮液加入DMSO中,浓度为0.05 ~ 5000μg /平板。番茄红素对鼠伤寒沙门氏菌TA98、TA100、TA1535和TA1537以及有无S-9混合物的大肠杆菌WP2uvrA-均无明显的致突发性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of the Mutagenicity of Lycopene by the Ames Test.
Lycopene is a hydrocarbon carotenoid in tomato products. We examined the mutagenicity of lycopene by the Ames test, to evaluate the safety of lycopene. Lycopene extracted from tomato paste was added as a solution or suspension in DMSO at 0.05-5000μg per plate. Lycopene showed no detectable mutagenicity on Salmonella typhimurium TA98, TA100, TA1535 and TA1537, and Escherichia coli WP2uvrA- with or without S-9 mix.
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