铽放射性核素在治疗学上的应用:以医学为重点

R. Formento Cavaier , F. Haddad , T. Sounalet , T. Stora , I. Zahi
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引用次数: 33

摘要

一个名为CERN- medicis的新设施正在CERN建造,以生产用于医疗用途的放射性核素。与此同时,欧洲核子研究中心正在协调欧洲委员会地平线2020计划的玛丽·斯克洛多夫斯卡-居里创新培训网络MEDICIS-PROMED,以培训年轻科学家生产和使用创新放射性核素,并在欧洲建立一个专家网络。MEDICIS-PROMED的一个项目是确定使用商用中型大电流回旋加速器和CERN-MEDICIS开发的质量分离技术为治疗学生产创新放射性同位素的可行性。这将允许生产高比活度放射性同位素,这是通过化学分离的普通后处理无法实现的。已鉴定出钪、铜、砷和铽的放射性同位素。本文将对生产Tb-149的活化产率和辐照参数优化进行初步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Terbium Radionuclides for Theranostics Applications: A Focus On MEDICIS-PROMED

A new facility, named CERN-MEDICIS, is under construction at CERN to produce radionuclides for medical applications. In parallel, the MEDICIS-PROMED, a Marie Sklodowska-Curie innovative training network of the Horizon 2020 European Commission‘s program, is being coordinated by CERN to train young scientists on the production and use of innovative radionuclides and develop a network of experts within Europe. One program within MEDICIS-PROMED is to determine the feasibility of producing innovative radioisotopes for theranostics using a commercial middle-sized high-current cyclotron and the mass separation technology developed at CERN-MEDICIS. This will allow the production of high specific activity radioisotopes not achievable with the common post-processing by chemical separation. Radioisotopes of scandium, copper, arsenic and terbium have been identified. Preliminary studies of activation yield and irradiation parameters optimization for the production of Tb-149 will be described.

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